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Dust Exposure, Fractional Exhaled Nitric Oxide and Respiratory Symptoms among Volcanic Rock Miners in Kilimanjaro, Tanzania Cover

Dust Exposure, Fractional Exhaled Nitric Oxide and Respiratory Symptoms among Volcanic Rock Miners in Kilimanjaro, Tanzania

Open Access
|Aug 2018

Figures & Tables

Table 1

Socio demographic characteristics of study population.

CharacteristicsVolcanic stone workers (n = 70)Controls (n = 65)
Age Mean(SD) (years)33.6(12.3)34.2(13.6)
Education level, Mean(SD)6.9(1.7)9.4(2.9)
Tenure Mean(SD) years)7.8(6.7)6.0(5.9)
Sex n (%)
  Male62(88.6)53(81.5)
  Female8(42.9)12(18.5)
Smoking n (%)
  Current smoker21(30)9(41)*
  Non smoker49(70)56(86)
Table 2

Distribution of mean dust concentrations for workers in Rongoma, Pumwani, Kawawa and Uchira volcanic mines.

PlaceNMean(SD)MedianMinimumMaximum
Rongoma102.76(3.86)1.140.3912.23
Pumwani109.00(5.83)8.752.1020.84
Kawawa Kiuo50.63(0.44).630.151.20
Uchira30.57(0.48).440.171.11
Total284.371.440.1520.84
Table 3

Prevalence of Chronic respiratory symptoms by exposure status among volcanic miners.

Reported SymptomsExposed (n = 70)Controls (n = 65)p-value#
Morning cough13(18.6)4(6.2)0.651
Cough day & night21(30.0)4(6.2)0.058
Morning cough with sputum10(14.3)4(6.2)0.038
Cough day & night with sputum14(20)2(3.1)0.003
Chest tightness17(24.6)1(1.5)0.001
Wheezing20(28.6)5(7.7)0.002
Dyspnoea 121(30.0%)3(4.6)0.003
Dyspnoea 211(15.7%)1(1.5)0.014
Dyspnoea 37(10.0%)0(0)

[i] # Fischer’s exact.

Table 4

Acute respiratory symptoms by exposure status among volcanic miners.

Reported SymptomsExposed (n = 69)Controls (n = 21)Totalp-value*
Acute cough23(34.8%)2(10.0%)25(29.1%)0.032*
Acute dyspnoea13(18.8%)1(4.8%)14(15.6%)0.131*
Acute wheezing12(17.4%)2(9.5%)14(15.6%)0.612
Sneezing33(47.8%)6(28.6%)40(44.4%)0.119
Red eyes31(44.9%)3(14.3%)35(38.9%)0.011
Itching eyes28(41.2%)4(19.0%)32(36.0%)0.174

[i] *Fischer’s exact test.

Table 5

Distribution of Exhaled nitrogen oxide among non-smokers study population by exposure status and gender.

SexExposure statusMean (SD) ppbWork categoryMean (SD) ppb
MaleExposed (n = 36)27.89(19.14)Stone cutter28.8(19.59)
Control (n = 25)16.88(9.19)Transportation15.80(5.33)
Control16.70(8.53)
FemaleExposed (n = 2)16.50(4.95)
Control (n = 14)14.93(5.12)
TotalExposed (N = 38)27.29(18.81)
Control (N = 39)16.18(7.95)
Table 6

Multiple regression analysis of the FeNO values by exposure status.

ModelUnstandardized CoefficientsStandardized CoefficientsSig.95% Confidence Interval for B
BStd. ErrorBetaLower BoundUpper Bound
R2 = 13.5%(Constant)25.5347.108.00111.41039.658
Age–.082.125–.066.510–.330.165
Sex–4.4253.935–.115.264–12.2453.394
Exposed and controls (1/0)9.1013.034.309.0043.07215.129
Table 7

Odds ratio for development of respiratory symptoms among volcanic stone cutters.

SymptomsOdds Ratio (95%CI)Adjusted Odds ratiop-value
Morning cough3.5(1.7–11.3)1.8(0.5–7.0)0.370
Day and Night6.5(2.1–20.3)3.9(1.3–14.1)0.034
Wheezing4.8(1.7–13.7)3.1(0.9–10.0)0.064
DOI: https://doi.org/10.29024/aogh.2320 | Journal eISSN: 2214-9996
Language: English
Published on: Aug 31, 2018
Published by: Levy Library Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2018 Simon Mamuya, Gloria Sakwari, Vera Ngowi, Bente Moen, Magne Bråtveit, published by Levy Library Press
This work is licensed under the Creative Commons Attribution 4.0 License.