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Evaluation of Benzene Exposure and Early Biomarkers of Kidney Damage in Children Exposed to Solvents Due to Precarious Work in Ticul, Yucatán, México Cover

Evaluation of Benzene Exposure and Early Biomarkers of Kidney Damage in Children Exposed to Solvents Due to Precarious Work in Ticul, Yucatán, México

Open Access
|Jul 2019

Figures & Tables

Table 1

Descriptive characteristics of children from Ticul.

Characteristics
Children (N)41
Boys (%)44
Age (years)8.5 ± 2.5
Height (cm)129.4 ± 12.5
Weight (Kg)30.8 ± 9.8
BMI (Kg/m2) (%)
      Underweight65
      Normal weight29
      Overweight6
Height for age (Z-Score H/A)# %
      Moderate chronic undernutrition (<–2)9
      Severe chronic undernutrition (<–3)3
Weight for age (Z-Score W/A)# %
      Overweight (>1)33
      Acute moderate malnutrition (<–2)9
Child burden* (%)15
Home/workplace° (%)44
Drinking water (%)20

[i] # Calculated by Z ranges of child growth standards proposed by the World Health Organization (WHO).

* Children who study and work.

° Children whose workplace is inside the house they inhabit.

Table 2

Levels of benzene exposure.

WorkplaceMeanSDP25P50P75BEI&
Inside (N = 18)0.591.09<LOD0.060.6728
Outside (N = 23)0.200.38<LOD0.000030.2317

[i] Units expressed in mg tt-MA/g creatinine. & BEI; Biological exposure index (0.5 mg/g creatinine), expressed as percentage. * Limit of detection (LOD) for tt-MA was approximately 0.05 μ g/L. SD (Standar Deviation), P25, P50 and P75 (percentile).

Table 3

Urinary levels of renal damage biomarkers of Ticul children.

Inside (N = 18)Outside (N = 23)
ParametersMeanSDP25P50P75MeanSDP25P50P75
NGAL**12.925.13.04.711.710.111.52.95.212.5
Albuminuria*25.632.610.010.030.013.57.810.010.010.0
Cys-C**12.910.93.711.819.59.26.43.97.513.6
OPN**213.7126.095.5224.4331.4227.7114.6166.8226.5295.3
α1-MG**115.265.663.696.6176.095.258.250.573.6144.9

[i] NGAL: Neutrophil gelatinase-associated lipocalin. Cys-C: cystatin-C. OPN: Osteopontin. a1-MG: α 1-Microglobulin. Mean, SD (Standar Deviation), P25, P50 and P75 (percentile) as: * mg/l and ** ng/ml.

DOI: https://doi.org/10.5334/aogh.2482 | Journal eISSN: 2214-9996
Language: English
Published on: Jul 3, 2019
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2019 Norma Pérez-Herrera, Lorena Díaz de León-Martínez, Rogelio Flores-Ramírez, Olivier Barbier, Manolo Ortega-Romero, Fernando May-Euán, Kelvin Saldaña-Villanueva, Javier Perera-Rios, Francisco Javier Pérez-Vázquez, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.