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Pyrethroid Insecticides in Households from Urban Areas: An Association of the 3-PBA Metabolite and Hand Wipes Cover

Pyrethroid Insecticides in Households from Urban Areas: An Association of the 3-PBA Metabolite and Hand Wipes

Open Access
|Jun 2020

Figures & Tables

Table 1

Characteristics and factors exposure in children of 2–3 years from Bangkok households (N = 80).

Characteristics/factors exposuren (%) or (median ± SD)
Children and parent information
        Aged (months)36.00 ± 11.15
        Weight (kg)13.6 ± 4.7
Gender
        Male28 (35)
        Female52 (65)
Parents education level
        Illiterate8 (10.0)
        ≥Primary school72 (90.0)
Occupational status
        No Work60 (75.0)
        Work20 (25.0)
Care giver of children
        Others50 (62.5)
        Mother30 (37.5)
Exposure characteristics
Type of PYR insecticide use
        Others insecticide13 (16.3)
        Coil insecticide67 (83.8)
Frequency of PYR insecticide use in household (times/month)
        Some time17 (21.3)
        Every day63 (78.8)
Storage PYR insecticide products
        Outside household13 (16.2)
        Inside household67 (83.8)
Frequency of floor-cleaning
        Never28 (35.0)
        Once a week52 (65.0)
Type floor cleaning
        Non-wet broom28 (35.0)
        Wet broom52 (65.0)
Children’s personal exposure
Children play of the floor in household
        No
        Yes
Children play soil during the in household
        No
        Yes
Children walk bare feet inside household
        No18 (22.5)
        Yes62 (77.5)
Children wash their hands/feet during the day
        No33 (41.3)
        Yes47 (58.8)
Children take a shower during the day
        1–2 times38 (47.5)
        >2 times42 (52.5)
Children put hand-to-mouth
        No12 (15.0)
        Yes67 (83.8)
Children put object-to-mouth
        No14 (17.5)
        Yes66 (82.5)
Children put finger-to-mouth
        No18 (22.5)
        Yes62 (77.5)
Eating on the floor
        No14 (17.5)
        Yes66 (82.5)
Washing fruits
        No28 (35)
        Yes52 (65)
Home characteristics
Type of household
        Non permanency28 (35)
        Permanency52 (65)
Main type floor
        Non cement floor28 (35)
        Cement floor52 (65)
Table 2

The 3-PBA metabolite and hand wipes concentration in children of 2–3 years (n = 80) from Bangkok households.

BiomarkersConcentration
MedianMean ± SDRangeDetected (%)
3-PBA (µg/mL)a1.4601.470 ± 0.0840.231–2.53492
Hand wipes (µg/mL)b
      Cypermethrin0.01710.016 ± 0.00490.021–0.00592

[i] a Method detection limits (MDLs) = 0.01 µg/mL.

b Method detection limits (MDLs) = 0.001 µg/mL.

Table 3

The correlation between 3-PBA metabolite and hand wipes sample of 2–3-year-old children (n = 80) from Bangkok households.

Urine sampleSpearman’s coefficient (rs)
3-PBACypermethrin
3-PBA (µg/mL)1.000  
Hand wipes (µg/mL)
      Cypermethrin0.226*1.000

[i] * Correlation coefficient significant at p < 0.05.

Table 4

Multivariate analysis of factor’s exposure with 3-PBA metabolites concentration on urine children (n = 80) from Bangkok households.

Multi-factors exposureBS.E.Waldp-ValueOR (95% CI)
Aged (months)–0.0080.0230.1240.725  0.992 (0.949–1.037)
Gendera–1.1200.5324.4280.035*0.326 (0.115–0.926)
Walk bare feet inside householdb1.9561.4183.9830.007*7.072 (1.707–29.291)

[i] 3-PBA metabolite concentration in urine (Low = ≤ 1.46 µg/mL, High = ≥ 1.46 µg/mL). B, regression coefficient; S.E., standard error; OR, odds ratio; CI, confidence interval. Reference category: first. a 0 = male, 1 = female. b 0 = no, 1 = yes. *Significant at p < 0.05.

Table 5

Multivariate analysis of factor’s exposure with hand wipe sample (Cypermethrin) in children (n = 80) from Bangkok households.

Multi-factors exposureBS.E.Waldp-ValueOR (95% CI)
Aged (months)0.0190.0230.6770.4111.019 (0.974–1.066)
Gendera0.7220.5531.7000.1922.058 (0.696–6.087)
Walk bare feet inside householdb0.8250.8940.8520.3562.282 (0.396–13.166)
Play of the floor in householdb0.7620.9140.6960.4042.143 (0.357–12.851)
Play soil during the in householdb1.4321.0831.7480.1864.189 (0.501–35.015)

[i] 3-PBA metabolite concentration in urine (Low = ≤0.0171 µg/mL, High = ≥0.0171 µg/mL). B, regression coefficient; S.E., standard error; OR, odds ratio; CI, confidence interval. Reference category: first. a 0 = male, 1 = female. b 0 = no, 1 = yes. * Significant at p < 0.05.

DOI: https://doi.org/10.5334/aogh.2746 | Journal eISSN: 2214-9996
Language: English
Published on: Jun 5, 2020
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2020 Jadsada Kunno, Parichat Ong-artborirak, Pongsaya Panicharoen, Mark Gregory Robson, Wattasit Siriwong, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.