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Implementing Advanced HIV Disease Care for Inpatients in a Referral Hospital in Malawi – Demand, Results and Cost Implications Cover

Implementing Advanced HIV Disease Care for Inpatients in a Referral Hospital in Malawi – Demand, Results and Cost Implications

Open Access
|Mar 2022

Figures & Tables

Table 1

HIV testing in medical wards and advanced HIV disease test data for KCH inpatients (January to December).

20172020
Admissions66453340
Early death880 (13.2%)390 (11.7%)
Early discharge391 (5.9%)302 (9.0%)
On previous ART1614638
Eligible for testing37602010
Tested3389 (90.1%)1549 (77.1%)
HIV positive240 (7.1%)69 (4.5%)
CD4 done583460
CD4 < 200n.a.245 (53.3%)
CD4 < 100230 (39.4%)147 (31.9%)
CrAg test done185238
CrAg positive20 (10.8%)39 (16.4%)
LAM tests done298219
LAM positive69 (23.1%)62 (28.3%)
Table 2

Characteristics of ART and TB patients newly starting treatment as inpatients in KCH wards (January to December).

20172020
ART PATIENTS INITIATEDTB TREATMENT INITIALEDART PATIENTS INITIATEDTB TREATMENT INITIALED
Total274306117201
Male124 (45.2%)173 (56.6%)54 (46.2%)116 (57.7%)
Female150 (54.8%)133 (43.4%)63 (53.8%)85 (42.3%)
Age <209 (3.2%)15 (4.9%)11 (9.4%)9 (4.5%)
20–50234 (85.5%)250 (81.7%)101 (86.3%)151 (75.1%)
>5031 (11.3%)41 (13.4%)5 (4.3%)41 (20.4%)
Medical ward204 (74.4%)90 (76.9%)
Other ward70 (25.6%)27 (23.1%)
WHO stage 1/2167 (60.9%)81 (69.2%)
WHO Stage 3/4107 (30.1%)36 (30.8%)
PTB only86 (28.1%)26 (12.9%)
EPTB (+/–PTB)220 (71.9%)175 (87.1%)
HIV positive243 (79.4%)156 (77.6%)
HIV negative63 (20.6%)45 (22.4%)
Table 3

Correlation of Urine-LAM and FASH ultrasound results in medical inpatients receiving both tests.

FASH +FASH –
U-LAM+17 (12.6%)21 (15.7%)38
U-LAM–28 (20.9%)68 (50.7%)96
4589134

[i] % of agreement: 63.23%, Cohen’s k: 0.15 (Slight agreement).

Table 4

Cost analysis of the Lighthouse inpatient AHD support program 2020.

NITEM COST (USD)
ROOM AND EQUIPMENT (CAPITAL INVESTMENT)TOTAL/5 YEAR PERIOD
Roomin kind Dept. of Medicine
Face lifting and security upgrade (burglar bars, new locks etc.)1400$400
EMRS screen, label printer11 063$1 063
PIMA CD4 count analyzer18 995$8 995
Other items (furniture, BP machine, scale, fan etc.)1250$250
Total$10 708
Annual subtotal$2 142/year
STAFF SALARYTOTAL/YEAR
LH HIV counselor (per year)15 800$5 800#
LH nurse (per year)117 000$17 000*
LH clinical officer (per year)0.2518 800$4 700
Subtotal$27 500/year
TESTS
HIV rapid tests15491$1 549#
HIV confirmation tests1502$300#
CD4 tests5338.4$4 472*
CD4 PIMA beads for calibration259.1$118*
CrAg tests2712.8$759**
LAM tests2624.6$1 205***
EDTA tubes and needles6000.2$120*
Creatinine, potassium and FBC monitoring (twice per CM treatment)1185$590&
Subtotal$9 113/year
DRUGS
ART and CPTpart of long-term care (through Dept. HIV/AIDS)
RHZE and Vit B6part of long-term care (through Nat. TB program)
Fluconazolepart of long-term care (through Dept. HIV/AIDS)
Liposomal AmphothericinB (per course)59186.9$11 027&
Flucytosine (per course)5986.2$5 086&
Subtotal$16 113/year
OTHER CONSUMABLES
Registers, stationary etc. per month1225$300
Total$62 139/year (= $5.178/month)

[i] # Cost of HIV testing, * cost of CD4 testing, ** cost of CrAg, *** cost of LAM, & cost of CM treatment.

Table 5

Cost of individual test and results obtained.

TEST AND RESULT TYPETOTAL COSTNCOST/CLIENT
HIV test doneUS$ 7 6491,549US$ 4.9
HIV positive patient identifiedUS$ 7 64969US$ 110.8
CD4 test done (nurse time fully excluded)US$ 4 715533US$ 8.8
CD4 test done (nurse time fully included)US$ 21 715533US$ 40.7
CD4 < 200 identified (nurse time fully excluded)US$ 4 715275US$ 17.1
CD4 < 200 identified (nurse time fully included)US$ 21 715275US$ 78.9
Positive serum CrAg resultUS$ 75941US$ 18.5
Positive urine LAM resultUS$ 1 20569US$ 17.5
CM Patient treated w AmpB/FluCUS$ 16 70359US$ 283.1
DOI: https://doi.org/10.5334/aogh.3532 | Journal eISSN: 2214-9996
Language: English
Published on: Mar 8, 2022
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2022 Tom Heller, Douglas Damba, Tapiwa Kumwenda, Jacqueline Huwa, Christine Kamamia, Angellina Nhlema, Claudia Wallrauch, Chimwemwe Chawinga, Cecilia Kanyama, Lillian Gondwe-Chunda, Jonathan Ngoma, Beatrice Matanje, Hannock Tweya, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.