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Cardiovascular Mortality During the COVID-19 Pandemics in a Large Brazilian City: A Comprehensive Analysis Cover

Cardiovascular Mortality During the COVID-19 Pandemics in a Large Brazilian City: A Comprehensive Analysis

Open Access
|Feb 2022

Figures & Tables

Table 1

Age-standardized rates per 100,000 inhabitants or proportions and their 95% confidence intervals for cardiovascular disease outcomes observed in 2020 and expected (mean of 2015–2019) for epidemiological weeks 10–48, their absolute difference, and risk ratio with 95% confidence intervals. Belo Horizonte, MG, Brazil.

OBSERVED (95% CI)EXPECTED(95% CI)ABSOLUTE DIFFERENCERISK RATIO (95% CI)
Deaths
CVD247 (238;256)245 (236;254)2.01.01 (0.96;1.06)
ACS41 (37;44)40 (37;44)0.21 (0.88;1.14)
Stroke60 (56;65)61 (56;65)–0.50.99 (0.89;1.1)
HF24 (21;27)18 (15;20)5.91.32 (1.1;1.59)*
Deaths at Home
CVD84 (78;89)63 (59;68)20.61.32 (1.2;1.46)*
ACS10 (8;12)7 (6;9)2.81.38 (1.04;1.82)*
Stroke9 (7;11)7 (6;9)1.71.22 (0.92;1.63)
HF8 (7;10)5 (4;7)3.01.53 (1.12;2.1)*
Hospital Admissions
CVD782 (766;799)1026 (1008;1045)–244.00.76 (0.74;0.78)*
ACS176 (169;184)222 (214;231)–45.80.79 (0.75;0.84)*
Stroke153 (146;160)148 (141;155)5.51.04 (0.97;1.11)*
HF161 (154;169)168 (160;175)–6.40.96 (0.9;1.02)
ICU Admissions
CVD299 (289;309)341 (330;352)–41.60.88 (0.84;0.92)*
ACS127 (121;134)155 (148;163)–28.40.82 (0.76;0.88)*
Stroke48 (44;52)41 (37;45)7.41.18 (1.04;1.33)*
HF45 (42;50)43 (39;47)2.81.06 (0.94;1.21)
% ICU Admissions
CVD38 (37;39)33 (32;34)5.01.15 (1.1;1.21)*
ACS72 (70;74)70 (68;71)2.11.03 (0.96;1.1)
Stroke31 (29;33)27 (25;29)3.81.14 (1.01;1.29)*
HF28 (26;30)25 (23;27)2.81.11 (0.98;1.25)
In-Hospital Deaths
CVD49 (45;54)56 (51;60)–6.30.89 (0.79;0.99) *
ACS7 (5;8)9 (7;11)–2.20.76 (0.57;1.01)
Stroke16 (14;18)17 (14;19)–0.70.96 (0.79;1.18)
HF13 (11;15)12 (10;14)0.51.04 (0.83;1.31)
% In-Hospital Deaths
CVD6 (5;6)5 (5;5)0.91.16 (1.04;1.3)*
ACS4 (3;4)4 (3;5)–0.20.96 (0.71;1.28)
Stroke10 (9;12)11 (9;13)–0.80.93 (0.76;1.13)
HF8 (6;9)7 (6;8)0.61.08 (0.86;1.36)

[i] ACS: acute coronary syndrome, CI: confidence intervals, CVD: cardiovascular disease, HF: heart failure, ICU: intensive care unit.

Table 2

Risk ratios for total cardiovascular disease outcomes and their 95% confidence intervals in subgroup analysis, according to sex, age group, health vulnerability, and pandemic phase, in Belo Horizonte, Brazil, from epidemiological weeks 10–48, 2020, compared to the mean of epidemiological weeks 10–48, 2015–2019.

DEATHSDEATHS AT HOME% DEATHS AT HOMEHOSP. ADMISSIONSICU% ICUIN-HOSPITAL DEATHS% IN-HOSPITAL DEATHS
Sex
Female0.98 (0.91;1.06)1.35 (1.17;1.56)*1.35 (1.17;1.56)*0.69 (0.66;0.72)*0.87 (0.81;0.94)*1.26 (1.17;1.35)*0.86 (0.73;1.02)1.2(1.02;1.42)*
Male1.04 (0.97;1.11)1.29 (1.13;1.47)*1.27 (1.11;1.44)*0.84 (0.81;0.87)*0.88 (0.83;0.94)*1.05 (0.99;1.12)0.91 (0.78;1.06)1.14(0.98;1.32)
Age Groups
30–590.91 (0.79;1.04)1.09 (0.85;1.4)1.2 (0.93;1.54)0.66 (0.63;0.69)*0.86 (0.79;0.92)*1.29 (1.19;1.39)*0.8(0.63;1.01)1.2(0.95;1.53)
60+1.03 (0.97;1.09)1.37 (1.23;1.52)*1.33 (1.2;1.48)*0.83 (0.8;0.86)*0.89 (0.84;0.94)*1.07 (1.01;1.14)*0.91(0.8;1.04)1.1(0.97;1.25)
Vulnerability
Low0.95 (0.86;1.05)1.21 (1.01;1.45)*1.25 (1.04;1.49)*0.72 (0.67;0.78)*0.82 (0.73;0.92)*1.12 (0.99;1.26)1.02(0.76;1.38)1.32(0.98;1.79)
Medium1.01 (0.93;1.09)1.32 (1.13;1.53)*1.32 (1.13;1.53)*0.76 (0.73;0.79)*0.89 (0.83;0.95)*1.18 (1.1;1.26)*0.88 (0.75;1.03)1.2(1.03;1.41)*
High1.04 (0.94;1.14)1.45 (1.21;1.74)*1.41 (1.17;1.69)*0.81 (0.78;0.85)*0.9 (0.84;0.97)*1.13 (1.05;1.21)*0.82 (0.69;0.99)*1.13(0.95;1.36)
Pandemic Phase
1° Period1.01 (0.92;1.12)1.37 (1.15;1.63)*1.35 (1.13;1.6)*0.77 (0.73;0.81)*1.03 (0.95;1.12)1.34 (1.24;1.45)*0.87(0.7;1.06)1.12(0.91;1.38)
2° Period0.96 (0.86;1.06)1.35 (1.11;1.63)*1.4 (1.16;1.7)*0.75 (0.71;0.8)*0.8 (0.73;0.89)*1.07 (0.97;1.18)0.81 (0.64;1.02)1.07(0.85;1.36)
3° Period1.03 (0.95;1.12)1.28 (1.1;1.48)*1.24 (1.07;1.44)*0.76 (0.73;0.8)*0.82 (0.76;0.87)*1.07 (1;1.14)0.95(0.8;1.11)1.24(1.05;1.46)*

[i] ICU: intensive care unit.

Figure 1

Age-standardized death, death at home, and in-hospital death rates per 100,000 inhabitants, for cardiovascular diseases, observed in 2020 and expected (mean of 2015–2019) for epidemiological weeks 10–48, with 95% confidence intervals. Belo Horizonte, MG, Brazil.

Figure 2

Risk ratios expected (mean of 2015–2019) and observed in 2020 for age-standardized rates per 100,000 inhabitants or proportions for cardiovascular disease outcomes for epidemiological weeks 10–48. Belo Horizonte, MG, Brazil.

DOI: https://doi.org/10.5334/gh.1101 | Journal eISSN: 2211-8179
Language: English
Submitted on: Jan 26, 2022
Accepted on: Feb 1, 2022
Published on: Feb 21, 2022
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2022 Luisa C. C. Brant, Pedro C. Pinheiro, Antonio L. P. Ribeiro, Isis E. Machado, Paulo R. L. Correa, Mayara R. Santos, Maria de Fatima Marinho de Souza, Deborah C. Malta, Valéria M. A. Passos, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.