Cardiovascular Risk Factors and Clinical Outcomes among Patients Hospitalized with COVID-19: Findings from the World Heart Federation COVID-19 Study
By: Dorairaj Prabhakaran, Kavita Singh, Dimple Kondal, Lana Raspail, Bishav Mohan, Toru Kato, Nizal Sarrafzadegan, Shamim Hayder Talukder, Shahin Akter, Mohammad Robed Amin, Fastone Goma, Juan Gomez-Mesa, Ntobeko Ntusi, Francisca Inofomoh, Surender Deora, Evgenii Philippov, Alla Svarovskaya, Alexandra Konradi, Aurelio Puentes, Okechukwu S. Ogah, Bojan Stanetic, Aurora Issa, Friedrich Thienemann, Dafsah Juzar, Ezequiel Zaidel, Sana Sheikh, Dike Ojji, Carolyn S.P. Lam, Junbo Ge, Amitava Banerjee, L. Kristin Newby, Antonio Luiz P. Ribeiro, Samuel Gidding, Fausto Pinto, Pablo Perel, Karen Sliwa and On Behalf of the WHF COVID-19 Study Collaborators
References
- Thienemann F, Pinto F, Grobbee DE, et al. World Heart Federation Briefing on Prevention: Coronavirus Disease 2019 (COVID-19) in Low-Income Countries. Glob Heart. 2020; 15(1): 31. [published Online first: 4 June 2020]. DOI: 10.5334/gh.778
- Hopman J, Allegranzi B, Mehtar S. Managing COVID-19 in Low- and Middle-Income Countries. JAMA. 2020; 323(16): 1549–50. [published Online first: 17 March 2020]. DOI: 10.1001/jama.2020.4169
- Angrup A, Kanaujia R, Ray P, et al. Healthcare facilities in low- and middle-income countries affected by COVID-19: Time to upgrade basic infection control and prevention practices. Indian J Med Microbiol. 2020; 38(2): 139–43. [published Online first: 05 September 2020]. DOI: 10.4103/ijmm.IJMM_20_125
- Grasselli G, Greco M, Zanella A, et al. Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy. JAMA Intern Med. 2020; 180(10): 1345–55. [published Online first: 16 July 2020]. DOI: 10.1001/jamainternmed.2020.3539
- Wiersinga WJ, Rhodes A, Cheng AC, et al. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review. JAMA. 2020; 324(8): 782–93. [published Online first: 11 July 2020]. DOI: 10.1001/jama.2020.12839
- O’Driscoll M, Ribeiro Dos Santos G, Wang L, et al. Age-specific mortality and immunity patterns of SARS-CoV-2. Nature. 2021; 590(7844): 140–45. [published Online first: 3 November 2020]. DOI: 10.1038/s41586-020-2918-0
- Verity R, Okell LC, Dorigatti I, et al. Estimates of the severity of coronavirus disease 2019: A model-based analysis. The Lancet Infectious Diseases. 2020; 20(6): 669–77. DOI: 10.1016/S1473-3099(20)30243-7
- Parasher A. COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment. Postgrad Med J. 2021; 97(1147): 312–20. [published Online first: 27 September 2020]. DOI: 10.1136/postgradmedj-2020-138577
- Yang X, Yu Y, Xu J, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: A single-centered, retrospective, observational study. The Lancet Respiratory Medicine. 2020; 8(5): 475–81. DOI: 10.1016/S2213-2600(20)30079-5
- Xiong T-Y, Redwood S, Prendergast B, et al. Coronaviruses and the cardiovascular system: Acute and long-term implications. Eur Heart J. 2020; 41(19): 1798–800. DOI: 10.1093/eurheartj/ehaa231
- Alharthy A, Aletreby W, Faqihi F, et al. Clinical Characteristics and Predictors of 28-Day Mortality in 352 Critically Ill Patients with COVID-19: A Retrospective Study. J Epidemiol Glob Health. 2021; 11(1): 98–104. [published Online first: 24 October 2020]. DOI: 10.2991/jegh.k.200928.001
- Adu-Amankwaah J, Mprah R, Adekunle AO, et al.The cardiovascular aspect of COVID-19. Ann Med. 2021; 53(1): 227–36. [published Online first: 22 December 2020]. DOI: 10.1080/07853890.2020.1861644
- Sliwa K, Singh K, Raspail L, et al. The World Heart Federation Global Study on COVID-19 and Cardiovascular Disease. Glob Heart. 2021; 16(1): 22. [published Online first: 28 May 2021]. DOI: 10.5334/gh.950
- Bank W. Poverty and Shared Prosperity 2020: Reversals of Fortune. 2020.
- Bukhman G, Mocumbi AO, Atun R, et al. The Lancet NCDI Poverty Commission: Bridging a gap in universal health coverage for the poorest billion. The Lancet. 2020; 396(10256): 991–1044. DOI: 10.1016/S0140-6736(20)31907-3
- World Bank county classification by income. (Accessed 04 January 2022).
https://datahelpdesk.worldbank.org/knowledgebase/articles/906519-world-bank-country-and-lending-groups . - Alkmim MB, Silva CBG, Figueira RM, et al. Brazilian National Service of Telediagnosis in Electrocardiography. Stud Health Technol Inform. 2019; 264: 1635–36. [published Online first: 24 August 2019]. DOI: 10.3233/shti190571
- Harris PA, Taylor R, Thielke R, et al. Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009; 42(2): 377–81. [published Online first: 22 October 2008]. DOI: 10.1016/j.jbi.2008.08.010
- Harris PA, Taylor R, Minor BL, et al. The REDCap consortium: Building an international community of software platform partners. J Biomed Inform. 2019; 95: 103208. [published Online first: 13 May 2019]. DOI: 10.1016/j.jbi.2019.103208
- Karp I. Re: ‘Estimating the relative risk in cohort studies and clinical trials of common outcomes’. Am J Epidemiol. 2014; 179(8): 1034–5. [published Online first: 21 February 2014]. DOI: 10.1093/aje/kwt435
- McNutt LA, Wu C, Xue X, et al. Estimating the relative risk in cohort studies and clinical trials of common outcomes. Am J Epidemiol. 2003; 157(10): 940–3. [published Online first: 15 May 2003]. DOI: 10.1093/aje/kwg074
- Zou G. A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol. 2004; 159(7): 702–6. [published Online first: 23 March2004]. DOI: 10.1093/aje/kwh090
- Dai CL, Kornilov SA, Roper RT, et al. Characteristics and Factors Associated with COVID-19 Infection, Hospitalization, and Mortality Across Race and Ethnicity. Clin Infect Dis; 2021. [published Online first: 21 February 2021]. DOI: 10.1093/cid/ciab154
- Acosta AM, Garg S, Pham H, et al. Racial and Ethnic Disparities in Rates of COVID-19-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death in the United States From March 2020 to February 2021. JAMA Netw Open. 2021; 4(10):
e2130479 . [published Online first: 22 October 2021]. DOI: 10.1001/jamanetworkopen.2021.30479 - Qureshi AI, Baskett WI, Huang W, et al. Effect of Race and Ethnicity on In-Hospital Mortality in Patients with COVID-19. Ethn Dis. 2021; 31(3): 389–98. [published Online first: 24 July 2021]. DOI: 10.18865/ed.31.3.389
- Xiong TY, Redwood S, Prendergast B, et al. Coronaviruses and the cardiovascular system: Acute and long-term implications. Eur Heart J. 2020; 41(19): 1798–800. [published Online first: 19 March 2020]. DOI: 10.1093/eurheartj/ehaa231
- Behrouzi B, Araujo Campoverde MV, Liang K, et al. Influenza Vaccination to Reduce Cardiovascular Morbidity and Mortality in Patients With COVID-19: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020; 76(15): 1777–94. [published Online first: 10 October 2020]. DOI: 10.1016/j.jacc.2020.08.028
- Yedlapati SH, Khan SU, Talluri S, et al. Effects of Influenza Vaccine on Mortality and Cardiovascular Outcomes in Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis. J Am Heart Assoc. 2021; 10(6):
e019636 . [published Online first: 16 March 2021]. DOI: 10.1161/JAHA.120.019636 - Udell JA, Zawi R, Bhatt DL, et al. Association between influenza vaccination and cardiovascular outcomes in high-risk patients: A meta-analysis. JAMA. 2013; 310(16): 1711–20. [published Online first: 24 October 2013]. DOI: 10.1001/jama.2013.279206
- Verma S, Saksena S, Sadri-Ardekani H. ACE2 receptor expression in testes: Implications in coronavirus disease 2019 pathogenesisdagger. Biol Reprod. 2020; 103(3): 449–51. [published Online first: 20 May 2020]. DOI: 10.1093/biolre/ioaa080
- Al-Benna S. Angiotensin-converting enzyme 2 gene expression in human male urological tissues: implications for pathogenesis and virus transmission pathways. Afr J Urol. 2021; 27(1): 89. [published Online first: 8 July 2021]. DOI: 10.1186/s12301-021-00192-4
- Prabhakaran D, Chandrasekaran AM, Singh K, et al. Yoga-Based Cardiac Rehabilitation After Acute Myocardial Infarction: A Randomized Trial. J Am Coll Cardiol. 2020; 75(13): 1551–61. [published Online first: 4 April 2020]. DOI: 10.1016/j.jacc.2020.01.050
- Dhakal BP, Sweitzer NK, Indik JH, et al. SARS-CoV-2 Infection and Cardiovascular Disease: COVID-19 Heart. Heart Lung Circ. 2020; 29(7): 973–87. [published Online first: 1 July 2020]. DOI: 10.1016/j.hlc.2020.05.101
- Nishiga M, Wang DW, Han Y, et al. COVID-19 and cardiovascular disease: From basic mechanisms to clinical perspectives. Nat Rev Cardiol. 2020; 17(9): 543–58. [published Online first: 22 July 2020]. DOI: 10.1038/s41569-020-0413-9
- Ma L, Song K, Huang Y. Coronavirus Disease-2019 (COVID-19) and Cardiovascular Complications. J Cardiothorac Vasc Anesth. 2021; 35(6): 1860–65. [published Online first: 27 May 2020]. DOI: 10.1053/j.jvca.2020.04.041
- Chang WT, Toh HS, Liao CT, et al. Cardiac Involvement of COVID-19: A Comprehensive Review. Am J Med Sci. 2021; 361(1): 14–22. [published Online first: 15 November 2020]. DOI: 10.1016/j.amjms.2020.10.002
- Shi S, Qin M, Shen B, et al. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiology. 2020; 5(7): 802–10. DOI: 10.1001/jamacardio.2020.0950
- Pareek M, Singh A, Vadlamani L, et al. Relation of Cardiovascular Risk Factors to Mortality and Cardiovascular Events in Hospitalized Patients With Coronavirus Disease 2019 (from the Yale COVID-19 Cardiovascular Registry). Am J Cardiol. 2021; 146: 99–106. [published Online first: 5 February 2021]. DOI: 10.1016/j.amjcard.2021.01.029
- Mehraeen E, Karimi A, Barzegary A, et al. Predictors of mortality in patients with COVID-19-a systematic review. Eur J Integr Med. 2020; 40: 101226. [published Online first: 27 October 2020]. DOI: 10.1016/j.eujim.2020.101226
- Wynants L, Van Calster B, Collins GS, et al. Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal. BMJ. 2020; 369: m1328. [published Online first: 9 April2020]. DOI: 10.1136/bmj.m1328
- Zhang JJY, Lee KS, Ang LW, et al. Risk Factors for Severe Disease and Efficacy of Treatment in Patients Infected With COVID-19: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis. Clin Infect Dis. 2020; 71(16): 2199–206. [published Online first: 15 May 2020]. DOI: 10.1093/cid/ciaa576
- Mesas AE, Cavero-Redondo I, Alvarez-Bueno C, et al. Predictors of in-hospital COVID-19 mortality: A comprehensive systematic review and meta-analysis exploring differences by age, sex and health conditions. PLoS One. 2020; 15(11):
e0241742 . [published Online first: 4 November 2020]. DOI: 10.1371/journal.pone.0241742 - Lippi G, Wong J, Henry BM. Hypertension in patients with coronavirus disease 2019 (COVID-19): a pooled analysis. Pol Arch Intern Med. 2020; 130(4): 304–09. [published Online first: 2 April 2020]. DOI: 10.20452/pamw.15272
- Mubarik S, Liu X, Eshak ES, et al. The Association of Hypertension With the Severity of and Mortality From the COVID-19 in the Early Stage of the Epidemic in Wuhan, China: A Multicenter Retrospective Cohort Study. Front Med (Lausanne). 2021; 8: 623608. [published Online first: 1 June 2021]. DOI: 10.3389/fmed.2021.623608
- Bian J, Li Z. Angiotensin-converting enzyme 2 (ACE2): SARS-CoV-2 receptor and RAS modulator. Acta Pharm Sin B. 2021; 11(1): 1–12. [published Online first: 20 October 2020]. DOI: 10.1016/j.apsb.2020.10.006
- Wu J, Deng W, Li S, et al. Advances in research on ACE2 as a receptor for 2019-nCoV. Cell Mol Life Sci. 2021; 78(2): 531–44. [published Online first: 12 August 2020]. DOI: 10.1007/s00018-020-03611-x
DOI: https://doi.org/10.5334/gh.1128 | Journal eISSN: 2211-8179
Language: English
Submitted on: Mar 13, 2022
Accepted on: May 19, 2022
Published on: Jun 15, 2022
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
© 2022 Dorairaj Prabhakaran, Kavita Singh, Dimple Kondal, Lana Raspail, Bishav Mohan, Toru Kato, Nizal Sarrafzadegan, Shamim Hayder Talukder, Shahin Akter, Mohammad Robed Amin, Fastone Goma, Juan Gomez-Mesa, Ntobeko Ntusi, Francisca Inofomoh, Surender Deora, Evgenii Philippov, Alla Svarovskaya, Alexandra Konradi, Aurelio Puentes, Okechukwu S. Ogah, Bojan Stanetic, Aurora Issa, Friedrich Thienemann, Dafsah Juzar, Ezequiel Zaidel, Sana Sheikh, Dike Ojji, Carolyn S.P. Lam, Junbo Ge, Amitava Banerjee, L. Kristin Newby, Antonio Luiz P. Ribeiro, Samuel Gidding, Fausto Pinto, Pablo Perel, Karen Sliwa, On Behalf of the WHF COVID-19 Study Collaborators, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.