Table 1
Demographic and clinical characteristics in relation to Survival at the last follow up.
| CHARACTER | OUTCOME | P-VALUE | ||
|---|---|---|---|---|
| ALIVE; 29 (39%) | DIED; 46 (61%) | TOTAL; 75 (100%) | ||
| Age at diagnosis in days; median (Inter quaternary range IQR) | 20 (6–30) | 25 (10–40) | 25 (8–40) | 0.346 |
| Age at the time of BAS in days (IQR) | 26 (9–44) | 30 (17–50) | 28 (10–50) | 0.424 |
| Age at the time of corrective surgery in days; median (IQR) | 90 (60–150) | 150 (90–240) | 90 (60–180) | 0.057* |
| Weight at the time of BAS in kg; mean (SD) | 3.3 (0.6) | 3.1 (0.4) | 3.2 (0.5) | 0.075 |
| Pre-BAS Oxygen Saturation (%); median (IQR) | 40 (40–50) | 50 (40–60) | 48 (40–60) | 0.049* |
| Post-BAS Oxygen Saturation (%); median (IQR) | 87 (85–90) | 87 (85–90) | 87 (85–90) | 0.326 |
| Oxygen saturation (%) improvement after BAS; median (IQR) | 45 (34–50) | 35 (30–45) | 40 (30–45) | 0.048* |
| Corrective surgery done | <0.001* | |||
| No | 2 (6%) | 34 (94%) | 36 (48%) | |
| Yes | 27 (69%) | 12 (31%) | 39 (52%) | |
| Type of corrective surgery | ||||
| Arterial switch | 13/39 (33 %) | 3/39 (8%) | 16/39 (41%) Primary arterial switch: 8 Staged arterial switch: 8 | |
| Atrial switch | 15/39 (38%) | 2/39 (5%) | 17/39 (44%) | |
| Unknown | 0 (0%) | 6/39 (15%) | 6/39 (15%) | |
| Duration between BAS and corrective surgery in days; median (IQR) | 60 (37–108) | 107 (86–210) | 67 (45–124) | 0.012* |
[i] *Statistically significant.
Figure 1
Timing of diagnosis and BAS in infants with TGA.
Figure 2
Difference between pre and post BAS oxygen saturation (%): red: early presenters, blue: late presenters, green: all patients.
Figure 3
Kaplan-Meier survival curves for infants with TGA, comparing those who underwent corrective surgery (blue) and those who did not (orange). The survival probability was significantly higher in the surgery group (p < 0.001). Median survival is not reached for those who underwent surgery, as majority of infants in this group survived for the entire study duration.