Skip to main content
Have a personal or library account? Click to login
Recent Advances on the Prevention and Management of Rheumatic Heart Disease Cover

Recent Advances on the Prevention and Management of Rheumatic Heart Disease

Open Access
|Feb 2025

Figures & Tables

Figure 1

The progress in vaccine research.

GAC, Group A Carbohydrate; SpeA, Streptococcal pyrogenic exotoxin A; SpeB, Streptococcal pyrogenic exotoxin B.

Table 1

Comparison of treatment options for rheumatic mitral valve disease: PMC, MVP, and MVR.

CATEGORYPMCMVPMVR
Advantages
  • - Minimally invasive.

  • - Faster recovery compared to surgical options.

  • - Suitable for severe mitral stenosis with favorable valve morphology.

  • - Lower early mortality rates compared to replacement.

  • - Preserves the patient’s native valve and ventricular function.

  • - Enhances long-term survival.

  • - Avoids long-term anticoagulation therapy, especially in pregnancies.

  • - Standardized surgical procedure with broad indications. Lower rate of reoperation compared to MVP.

  • - Durable solution for severely damaged valves.

Disadvantages
  • - Less effective in extremely severe cases or multivalvular diseases.

  • - Risk of restenosis over time.

  • - Long-term outcomes remain controversial, with possible need for reinterventions.

  • - Not always feasible for severely damaged valves.

  • - Requires long-term anticoagulation therapy for mechanical valves.

  • - Bioprosthetic valves have limited durability, especially for younger patients, and may require replacement.

  • - Higher risk of thrombotic complications in low-resource settings with poor INR monitoring.

Ideal Use Case
  • - Patients with severe mitral stenosis but without significant mitral regurgitation or heavy valve calcification.

  • - Patients with moderate to severe valve disease where repair is feasible, especially young patients or those needing preservation of valve function.

  • - Patients with severe valve damage unsuitable for repair, or those able to maintain effective anticoagulation management for mechanical valves.

[i] PMC, Percutaneous Mitral Commissurotomy; MVP, Mitral Valve Repair; MVR, Mitral Valve Replacement; INR, International Normalized Ratio.

DOI: https://doi.org/10.5334/gh.1402 | Journal eISSN: 2211-8179
Language: English
Submitted on: Aug 27, 2024
Accepted on: Feb 7, 2025
Published on: Feb 21, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Jiawen Zhang, Songhao Jia, Yuhe Chen, Jie Han, Hongjia Zhang, Wenjian Jiang, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.