Table 1
Demographic characteristics of the study population (n = 545,087).
| CHARACTERISTICS | STUDY DATA |
|---|---|
| Total participants, N | 545,087 |
| Median age (IQR) years | 45 (36–55) |
| Age distribution, n (%) | |
| <20 years | 8,087 (1.48) |
| 20–29 years | 4,6504 (8.53) |
| 30–39 years | 124,168 (22.77) |
| >40 years | 366,328 (67.20) |
| Gender, n (%) | |
| Male | 317,446 (58.23) |
| Female | 227,636 (41.76) |
Table 2
Familial Hypercholesterolemia Prevalence by Age and Gender in the primary data (n = 545,087).
| CATEGORY | FH CASES | N | PREVALENCE, % (95% CI) | PREVALENCE PER 1000 | PROPORTION | P VALUE |
|---|---|---|---|---|---|---|
| Overall | 2,991 | 545,087 | 0.55 (0.53–0.57) | 5.5 | 1:182 | |
| Gender | ||||||
| Male | 1,766 | 317,446 | 0.56 (0.53–0.58) | 5.6 | 1:180 | 0.66 |
| Female | 1,225 | 227,641 | 0.54 (0.51–0.57) | 5.4 | 1:185 | |
| Age groups | ||||||
| <20 years | 389 | 8,087 | 4.81 (4.35–5.30) | 48.1 | 1:21 | <0.01 |
| 20–29 years | 742 | 46,504 | 1.60 (1.48–1.71) | 16.0 | 1:63 | |
| 30–39 years | 864 | 124,168 | 0.70 (0.65–0.74) | 7.0 | 1:144 | |
| >40 years | 996 | 366,328 | 0.27 (0.26–0.29) | 2.7 | 1:368 | |
Figure 1
Map of Pakistan with district wise prevalence of FH. The black dots represent districts from which data was received. The red dots represent districts in which combined prevalence (present study and Farhad et al, 2023) was estimated. 1. Lahore (FH cases = 1236), 2. Karachi (FH cases = 1069), 3. Gujranwala (FH cases = 233), 4. Faisalabad (FH cases = 216), 5. Multan (FH cases = 170), 6. Hyderabad (FH cases = 159), 7. Rawalpindi (FH cases = 100), 8. Peshawar (FH cases = 86), 9. Larkana (FH cases = 69), 10. Rahim Yar Khan (FH cases = 62), 11. Sukkar (FH cases = 61).
Figure 2
Prevalence of FH in Pakistan in different groups based on age and gender. P value is for I2.
Figure 3
Map of South and Southeast Asian countries showing the prevalence of FH.