Integrated Care Using the ABCstroke Pathway Improves Cardiovascular Outcomes and Survival in Patients with First-Ever Ischaemic Stroke
References
- Buckley BJR, Harrison SL, Hill A, Underhill P, Lane DA, Lip GYH. Stroke-Heart Syndrome: Incidence and Clinical Outcomes of Cardiac Complications Following Stroke. Stroke. 2022;53(5):1759–63. DOI: 10.1161/STROKEAHA.121.037316
- Prosser J, MacGregor L, Lees KR, Diener HC, Hacke W, Davis S, et al. Predictors of early cardiac morbidity and mortality after ischemic stroke. Stroke. 2007;38(8):2295–302. DOI: 10.1161/STROKEAHA.106.471813
- Scheitz JF, Nolte CH, Doehner W, Hachinski V, Endres M. Stroke-heart syndrome: clinical presentation and underlying mechanisms. Lancet Neurol. 2018;17(12):1109–20. DOI: 10.1016/S1474-4422(18)30336-3
- Scheitz JF, Sposato LA, Schulz-Menger J, Nolte CH, Backs J, Endres M. Stroke-Heart Syndrome: Recent Advances and Challenges. J Am Heart Assoc. 2022;11(17):
e026528 . DOI: 10.1161/JAHA.122.026528 - Alqahtani F, Aljohani S, Tarabishy A, Busu T, Adcock A, Alkhouli M. Incidence and Outcomes of Myocardial Infarction in Patients Admitted With Acute Ischemic Stroke. Stroke. 2017;48(11):2931–8. DOI: 10.1161/STROKEAHA.117.018408
- Lettow I, Jensen M, Schlemm E, Boutitie F, Quandt F, Cheng B, et al. Serious Adverse Events and Their Impact on Functional Outcome in Acute Ischemic Stroke in the WAKE-UP Trial. Stroke. 2021;52(12):3768–76. DOI: 10.1161/STROKEAHA.120.033425
- Bucci T, Choi SE, Tsang CT, Yiu KH, Buckley BJ, Pignatelli P, et al. Incident dementia in ischaemic stroke patients with early cardiac complications: A propensity-score matched cohort study. Eur Stroke J. 2024:23969873241293573. DOI: 10.1177/23969873241293573
- Heuschmann PU, Kircher J, Nowe T, Dittrich R, Reiner Z, Cifkova R, et al. Control of main risk factors after ischaemic stroke across Europe: data from the stroke-specific module of the EUROASPIRE III survey. Eur J Prev Cardiol. 2015;22(10):1354–62. DOI: 10.1177/2047487314546825
- Mansoor H, Manion D, Swafford KJ, Jicha G, Moga D. National Trends of Vascular Risk Factor Control Among Stroke Survivors: From the National Health and Nutrition Examination Survey 2009 to 2020. J Am Heart Assoc. 2024;13(6):
e032916 . DOI: 10.1161/JAHA.123.032916 - Lip GYH, Lane DA, Lenarczyk R, Boriani G, Doehner W, Benjamin LA, et al. Integrated care for optimizing the management of stroke and associated heart disease: a position paper of the European Society of Cardiology Council on Stroke. Eur Heart J. 2022;43(26):2442–60. DOI: 10.1093/eurheartj/ehac245
- Wong AY, Root A, Douglas IJ, Chui CS, Chan EW, Ghebremichael-Weldeselassie Y, et al. Cardiovascular outcomes associated with use of clarithromycin: population based study. BMJ. 2016;352:
h6926 . DOI: 10.1136/bmj.h6926 - Chesnaye NC, Stel VS, Tripepi G, Dekker FW, Fu EL, Zoccali C, et al. An introduction to inverse probability of treatment weighting in observational research. Clin Kidney J. 2022;15(1):14–20. DOI: 10.1093/ckj/sfab158
- Pastori D, Pignatelli P, Menichelli D, Violi F, Lip GYH. Integrated Care Management of Patients With Atrial Fibrillation and Risk of Cardiovascular Events: The ABC (Atrial fibrillation Better Care) Pathway in the ATHERO-AF Study Cohort. Mayo Clin Proc. 2019;94(7):1261–7. DOI: 10.1016/j.mayocp.2018.10.022
- Yoon M, Yang PS, Jang E, Yu HT, Kim TH, Uhm JS, et al. Improved Population-Based Clinical Outcomes of Patients with Atrial Fibrillation by Compliance with the Simple ABC (Atrial Fibrillation Better Care) Pathway for Integrated Care Management: A Nationwide Cohort Study. Thromb Haemost. 2019;119(10):1695–703. DOI: 10.1055/s-0039-1693516
- Proietti M, Lip GYH, Laroche C, Fauchier L, Marin F, Nabauer M, et al. Relation of outcomes to ABC (Atrial Fibrillation Better Care) pathway adherent care in European patients with atrial fibrillation: an analysis from the ESC-EHRA EORP Atrial Fibrillation General Long-Term (AFGen LT) Registry. Europace. 2021;23(2):174–83. DOI: 10.1093/europace/euaa274
- Guo Y, Imberti JF, Kotalczyk A, Wang Y, Lip GYH. Atrial Fibrillation Better Care Pathway Adherent Care Improves Outcomes in Chinese Patients With Atrial Fibrillation. JACC Asia. 2022;2(4):422–9. DOI: 10.1016/j.jacasi.2022.01.007
- Proietti M, Romiti GF, Olshansky B, Lane DA, Lip GYH. Improved Outcomes by Integrated Care of Anticoagulated Patients with Atrial Fibrillation Using the Simple ABC (Atrial Fibrillation Better Care) Pathway. Am J Med. 2018;131(11):1359–66 e6. DOI: 10.1016/j.amjmed.2018.06.012
- Bucci T, Proietti M, Shantsila A, Romiti GF, Teo WS, Park HW, et al. Integrated Care for Atrial Fibrillation Using the ABC Pathway in the Prospective APHRS-AF Registry. JACC Asia. 2023;3(4):580–91. DOI: 10.1016/j.jacasi.2023.04.008
- Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomström-Lundqvist C, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). European Heart Journal. 2021;42(5):373–498. DOI: 10.1093/eurheartj/ehaa612
- Chao TF, Joung B, Takahashi Y, Lim TW, Choi EK, Chan YH, et al. 2021 Focused Update Consensus Guidelines of the Asia Pacific Heart Rhythm Society on Stroke Prevention in Atrial Fibrillation: Executive Summary. Thromb Haemost. 2022;122(1):20–47. DOI: 10.1055/s-0041-1739411
- Joung B, Lee JM, Lee KH, Kim T-H, Choi E-K, Lim W-H, et al. 2018 Korean Guideline of Atrial Fibrillation Management. Korean Circulation Journal. 2018;48(12):1033. DOI: 10.4070/kcj.2018.0339
- Buhari H, Fang J, Han L, Austin PC, Dorian P, Jackevicius CA, et al. Stroke risk in women with atrial fibrillation. Eur Heart J. 2024;45(2):104–13. DOI: 10.1093/eurheartj/ehad508
- Kumar S, Selim MH, Caplan LR. Medical complications after stroke. Lancet Neurol. 2010;9(1):105–18. DOI: 10.1016/S1474-4422(09)70266-2
- Sörös P, Hachinski V. Cardiovascular and neurological causes of sudden death after ischaemic stroke. Lancet Neurol. 2012;11(2):179–88. DOI: 10.1016/S1474-4422(11)70291-5
- Sposato LA, Hilz MJ, Aspberg S, Murthy SB, Bahit MC, Hsieh CY, et al. Post-Stroke Cardiovascular Complications and Neurogenic Cardiac Injury: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020;76(23):2768–85. DOI: 10.1016/j.jacc.2020.10.009
- Kallmunzer B, Breuer L, Kahl N, Bobinger T, Raaz-Schrauder D, Huttner HB, et al. Serious cardiac arrhythmias after stroke: incidence, time course, and predictors–a systematic, prospective analysis. Stroke. 2012;43(11):2892–7. DOI: 10.1161/STROKEAHA.112.664318
- Johnston KC, Li JY, Lyden PD, Hanson SK, Feasby TE, Adams RJ, et al. Medical and neurological complications of ischemic stroke: experience from the RANTTAS trial. RANTTAS Investigators. Stroke. 1998;29(2):447–53. DOI: 10.1161/01.STR.29.2.447
- Sagris D, Lip G, Korompoki E, Ntaios G, Vemmos K. Adherence to an integrated care pathway for stroke is associated with lower risk of major cardiovascular events: A report from the Athens Stroke Registry. Eur J Intern Med. 2024;122:61–7. DOI: 10.1016/j.ejim.2023.12.010
- Amarenco P, Bogousslavsky J, Callahan A,
3rd , Goldstein LB, Hennerici M, Rudolph AE, et al. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med. 2006;355(6):549–59. DOI: 10.1056/NEJMoa061894
DOI: https://doi.org/10.5334/gh.1430 | Journal eISSN: 2211-8179
Language: English
Submitted on: Oct 14, 2024
Accepted on: May 12, 2025
Published on: May 27, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
© 2025 Christopher T. W. Tsang, Sylvia E. Choi, Tommaso Bucci, Jia-Yi Huang, Qing-Wen Ren, Mei-Zhen Wu, Wen-Li Gu, Ran Guo, Jing-Nan Zhang, Anthony O. T. Ma, Steven H. M. Lam, Yap-Hang Chan, Kui-Kai Lau, Hung-Fat Tse, Azmil H. Abdul-Rahim, Gregory Y. H. Lip, Kai-Hang Yiu, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.