Cardiac Rehabilitation in Patients with Coronary Heart Disease – Provision, Attendance, and Outcomes: Results from the INTERASPIRE Survey from Fourteen Countries Across Six WHO Regions
By: Kornelia Kotseva, Dirk De Bacquer, Catriona Jennings, John William McEvoy, Lars Ryden, Kausik K. Ray, Gregory Y. H. Lip, Iris Erlund, Sandra Ganly, Terhi Vihervaara, Agnieszka Adamska, Ana Abreu, Wael Almahmeed, Ade Meidian Ambari, Susan Connolly, Junbo Ge, Irene Gibson, Hosam Hasan-Ali, Sue Hennessy, Yong Huo, Piotr Jankowski, Rodney M. Jimenez, Jennifer Jones, Yong Li, Ahmad Syadi Mahmood Zuhdi, Abel Makubi, Amam Chinyere Mbakwem, Lilian Mbau, Jose Luis Navarro Estrada, Okechukwu Samuel Ogah, Elijah Nyainda Ogola, Adalberto Quintero–Baiz, Mahmoud Umar Sani, Maria Ines Sosa Liprandi, Jack Wei Chieh Tan, David R Thompson, Miguel Alberto Urina Triana, Tee Joo Yeo, David Wood, Guy G. De Backer and on behalf of the INTERASPIRE Investigators
References
- Instutute for Health Metrics and Evaluation (IHME). Global Burden of Disease 2021: Findings from the GBD 2021 Study. Seattle, WA: IHME, 2024.
- Blacher J, Olié V, Gabet A, et al. Two-year prognosis and CVD prevention after acute coronary syndrome: The role of cardiac rehabilitation – a French nationwide study. Eur J Prev Cardiol. 2024;31:1939–1947. DOI: 10.1093/eurjpc/zwae194
- McMahon SR, Ades PA, Thompson PD. The role of cardiac rehabilitation in patients with heart disease. Trends Cardiovasc Med. 2017;27:420–425. DOI: 10.1016/j.tcm.2017.02.005
- Dibben G, Faulkner J, Oldridge N, et al. Exercise-based cardiac rehabilitation for coronary heart disease. Cochrane Database of Systematic Reviews. 2021;11:CD001800. DOI: 10.1002/14651858.CD001800.pub4
- Kotseva K, Wood D, De Bacquer D, et al, on behalf of the EUROASPIRE investigators. Determinants of participation and risk factor control according to attendance in cardiac rehabilitation programmes in coronary patients in Europe: EUROASPIRE IV survey. Eur J Prev Cardiol. 2018;25:1242–1251. DOI: 10.1177/2047487318781359
- Kotseva K, Wood D, De Backer G, De Bacquer D, on behalf of the EUROASPIRE III Study Group. Use and effects of cardiac rehabilitation in patients with coronary heart disease: Results from the EUROASPIRE III survey. Eur J Prev Cardiol. 2013;20:817–26. DOI: 10.1177/2047487312449591
- Norekvål TM, Bale M, Bedane HK, Hole T, Ingul CB, Munkhaugen J. Cardiac rehabilitation participation within 6 months of discharge in 37 136 myocardial infarction survivors: A nationwide registry study. Eur J Prev Cardiol. 2024;31:1977–1980. DOI: 10.1093/eurjpc/zwad350
- Grace SL, Hagström E, Harrison AS, et al, on behalf of the ICRR Investigators. Cardiac rehabilitation registries around the globe: Current status and future needs. Eur J Prev Cardiol. 2024;31:e117–e121. DOI: 10.1093/eurjpc/zwae182
- McEvoy JW, Jennings C, Kotseva K, et al, on behalf of the INTERASPIRE Investigators. INTERASPIRE: An international survey of coronary patients; their cardiometabolic, renal and biomarker status; and the quality of preventive care delivered in all WHO regions: in partnership with the World Heart Federation, European Society of Cardiology, Asia Pacific Society of Cardiology, InterAmerican Society of Cardiology, and PanAfrican Society of Cardiology. Curr Cardiol Rep. 2021;23:136. DOI: 10.1007/s11886-021-01568-2
- McEvoy JW, Jennings C, Kotseva K, et al, on behalf of the INTERASPIRE Investigators. Variation in secondary prevention of coronary heart disease: The INTERASPIRE study. Eur Heart J. 2024;45:4184–196. DOI: 10.1093/eurheartj/ehae558
- Taylor RS, Dalal HM, McDonagh STJ. The role of cardiac rehabilitation in improving cardiovascular outcomes. Nat Rev Cardiol. 2022;19:180–194. DOI: 10.1038/s41569-021-00611-7
- Anderson L, Oldridge N, Thompson DR, et al. Exercise-based cardiac rehabilitation for coronary heart disease: Cochrane systematic review and meta-analysis. J Am Coll Cardiol. 2016;67:1–12. DOI: 10.1016/j.jacc.2015.10.044
- Mahmood A, Ray R, Bin Salam ST, et al. The effectiveness of cardiac rehabilitation programs in improving cardiovascular outcomes: Systematic review and meta-analysis. Cureus. 2024;16(10):
e72450 . DOI: 10.7759/cureus.72450 - Salzwedel A, Jensen K, Rauch B, et al. Effectiveness of comprehensive cardiac rehabilitation in coronary artery disease patients treated according to contemporary evidence based medicine: Update of the Cardiac Rehabilitation Outcome Study (CROS-II). Eur J Prev Cardiol. 2020;27:1756–1774. DOI: 10.1177/2047487320905719
- Mamataz T, Uddin J, Ibn Alam S, et al, ACROSS collaboration. Effects of cardiac rehabilitation in low-and middle-income countries: A systematic review and meta-analysis of randomised controlled trials. Prog Cardiovasc Dis. 2022;70:119–174. DOI: 10.1016/j.pcad.2021.07.004
- Pesah E, Turk-Adawi K, Supervia M, et al. Cardiac rehabilitation delivery in low/middle-income countries. Heart. 2019;105:1806–12. DOI: 10.1136/heartjnl-2018-314486
- Visseren FLJ, Mach F, Smulders YM, et al. 2021 ESC guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021;42:3227–3337. DOI: 10.1093/eurheartj/ehab484
- Van Halewijn G, Deckers J, Tay HY, van Domburg R, Kotseva K, Wood D. Lessons from contemporary trials of cardiovascular prevention and rehabilitation: A systematic review and meta-analysis. Int J Cardiol. 2017;232:294–303. DOI: 10.1016/j.ijcard.2016.12.125
- Taylor R, Fredericks S, Jones I, et al. Global perspectives on heart disease rehabilitation and secondary prevention: A scientific statement from the Association of Cardiovascular Nursing and Allied Professions, European Association of Preventive Cardiology, and International Council of Cardiovascular Prevention and Rehabilitation. Eur Heart J. 2023;44:2515–2525. DOI: 10.1093/eurheartj/ehad225
- Samayoa L, et al. Sex differences in cardiac rehabilitation enrollment: A meta-analysis. Can J Cardiology. 2014;30:793–800. DOI: 10.1016/j.cjca.2013.11.007
- Silva V, Vilela EM, Campos L. Suboptimal control of cardiovascular risk factors in myocardial infarction survivors in a cardiac rehabilitation program. Rev Port Cardiol. 2021;40:911–920. DOI: 10.1016/j.repce.2021.11.007
- Zheng X, Zheng Y, Ma J, et al. Effect of exercise-based cardiac rehabilitation on anxiety and depression in patients with myocardial infarction: A systematic review and meta-analysis. Heart & Lung. 2019;48:1–7. DOI: 10.1016/j.hrtlng.2018.09.011
- Grace SL, Kotseva K, Whooley MA. Cardiac rehabilitation: Under-utilized globally. Current Cardiology Reports. 2021;23:118. DOI: 10.1007/s11886-021-01543-x
- Turk-Adawi K, Supervia M, Lopez-Jimenez F, et al. Cardiac rehabilitation availability and density around the globe. EClinicalMedicine. 2019;13:31–45. DOI: 10.1016/j.eclinm.2019.06.007
- Global Health Data Exchange. Institute for Health Metrics and Evaluation. GBD results tool.
http://ghdx.healthdata.org/gbd-results-tool ; 2021.
DOI: https://doi.org/10.5334/gh.1458 | Journal eISSN: 2211-8179
Language: English
Submitted on: May 10, 2025
Accepted on: Aug 4, 2025
Published on: Sep 2, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
© 2025 Kornelia Kotseva, Dirk De Bacquer, Catriona Jennings, John William McEvoy, Lars Ryden, Kausik K. Ray, Gregory Y. H. Lip, Iris Erlund, Sandra Ganly, Terhi Vihervaara, Agnieszka Adamska, Ana Abreu, Wael Almahmeed, Ade Meidian Ambari, Susan Connolly, Junbo Ge, Irene Gibson, Hosam Hasan-Ali, Sue Hennessy, Yong Huo, Piotr Jankowski, Rodney M. Jimenez, Jennifer Jones, Yong Li, Ahmad Syadi Mahmood Zuhdi, Abel Makubi, Amam Chinyere Mbakwem, Lilian Mbau, Jose Luis Navarro Estrada, Okechukwu Samuel Ogah, Elijah Nyainda Ogola, Adalberto Quintero–Baiz, Mahmoud Umar Sani, Maria Ines Sosa Liprandi, Jack Wei Chieh Tan, David R Thompson, Miguel Alberto Urina Triana, Tee Joo Yeo, David Wood, Guy G. De Backer, on behalf of the INTERASPIRE Investigators, published by Ubiquity Press
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