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Clinical Epidemiology of Hypertension in Rural Thailand: A Nationwide Cross-Sectional Study Cover

Clinical Epidemiology of Hypertension in Rural Thailand: A Nationwide Cross-Sectional Study

Open Access
|Dec 2025

Figures & Tables

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Table 1

Characteristics of study participants.

CHARACTERISTICSMENWOMENTOTAL
n = 317n = 6831000
n (%)n (%)n (%)
Sex distribution, %31.768.3
Age, years
    20–292 (0.6)1 (0.2)3 (0.3)
    30–397 (2.2)15 (2.2)22 (2.2)
    40–4920 (6.3)51 (7.5)71 (7.1)
    50–5965 (20.5)158 (23.1)223 (22.3)
    60–69115 (36.3)236 (34.6)351 (35.1)
    70–7987 (27.4)164 (24.0)251 (25.1)
    ≥8021 (6.6)58 (8.5)79 (7.9)
    mean (SD)64.3 (11.0)64.1 (11.2)64.2 (11.2)
    median (Q1–Q3)65.0 (58.0–72.0)65.0 (57.0–72.0)65.0 (57.0–72.0)
Geographical region
    Central78 (24.6)176 (25.8)254 (25.4)
    Northeast79 (24.9)167 (24.5)246 (24.6)
    North87 (27.4)165 (24.2)252 (25.2)
    South73 (23.0)175 (25.6)248 (24.8)
Health insurance scheme
    Universal health coverage278 (87.7)613 (89.8)891 (89.1)
    Civil servant medical benefits24 (7.6)53 (7.8)77 (7.7)
    Social security9 (2.8)10 (1.5)19 (1.9)
    Others6 (1.9)7 (1.0)13 (1.3)
Religion
    Buddhism292 (92.1)636 (93.1)928 (92.8)
    Christian19 (6.0)35 (5.1)54 (5.4)
    Islam6 (1.9)11 (1.6)17 (1.7)
    Others0 (0.0)1 (0.2)1 (0.1)
Marital status
    Married249 (78.6)425 (62.2)674 (67.4)
    Widowed33 (10.4)192 (28.1)225 (22.5)
    Divorced/separated15 (4.7)36 (5.3)51 (5.1)
    Never married20 (6.3)30 (4.4)50 (5.0)
Educational attainment
    Never attend29 (9.2)87 (12.7)116 (11.6)
    Nonformal2 (0.6)2 (0.3)4 (0.4)
    Grade 1–6213 (67.2)512 (75.0)725 (72.5)
    Grade 7–925 (7.9)35 (5.1)60 (6.0)
    Grade 10–1226 (8.2)32 (4.7)58 (5.8)
    Vocational13 (4.1)6 (0.9)19 (1.9)
    Bachelor’s degree or higher9 (2.8)9 (1.3)18 (1.8)
Occupation
    No occupation/retired113 (35.7)349 (51.1)462 (46.2)
    Agricultural workers143 (45.1)208 (30.5)351 (35.1)
    Seller22 (6.9)72 (10.5)94 (9.4)
    Homemaker2 (0.6)28 (4.1)30 (3.0)
    Service7 (2.2)8 (1.2)15 (1.5)
    Government officer5 (1.6)5 (0.7)10 (1.0)
    Mechanic8 (2.5)0 (0.0)8 (0.8)
    Professional3 (1.0)2 (0.3)5 (0.5)
    Priest4 (1.3)0 (0.0)4 (0.4)
    Others10 (3.2)11 (1.6)21 (2.1)
Household income, per year
    Under 50,000 Thai Baht142 (44.8)377 (55.2)519 (51.9)
    50,000–99,999 Baht78 (24.6)143 (20.9)221 (22.1)
    100,000–149,999 Baht41 (12.9)70 (10.3)111 (11.1)
    150,000–199,999 Baht13 (4.1)21 (3.1)34 (3.4)
    200,000–249,999 Baht13 (4.1)27 (4.0)40 (4.0)
    250,000–299,999 Baht3 (1.0)3 (0.4)6 (0.6)
    300,000 Baht and over14 (4.4)30 (4.4)44 (4.4)
    No intention to respond13 (4.1)12 (1.8)25 (2.5)
Duration of hypertension treatment, years
    1–372 (22.7)130 (19.0)202 (20.2)
    4–662 (19.6)122 (17.9)184 (18.4)
    7–986 (27.1)172 (25.2)258 (25.8)
    ≥1097 (30.6)259 (37.9)356 (35.6)
    mean (SD)8.0 (5.7)8.5 (5.1)8.3 (5.3)
    median (Q1–Q3)8.0 (4.0–11.0)8.0 (4.0–12.0)8.0 (4.0–11.0)
Systolic blood pressure, mmHg
    Mean (SD)134.5 (16.8)135.0 (17.0)134.8 (16.9)
    Median (Q1–Q3)132.3 (124.7–143.7)133.3 (123.3–144.3)133.0 (123.7–144.4)
Diastolic blood pressure, mmHg
    Mean (SD)77.2 (10.3)78.4 (10.5)77.6 (10.4)
    Median (Q1–Q3)76.3 (69.7–84.0)78.0 (71.0–84.7)76.7 (70.2–84.3)
Body mass index, kg/m2
    Mean (SD)24.2 (4.7)25.8 (5.1)25.3 (5.1)
    Median (Q1–Q3)23.7 (21.1–26.6)25.5 (22.3–28.5)24.8 (21.7–28.0)

[i] SD: standard deviation, Q1–Q3: interquartile range.

Figure 1

Prevalence of hypertension control among people with hypertension in rural Thailand in 2024, stratified by sex (A), age (B), and geographical region (C).

Table 2

Multivariable analysis for factors associated with hypertension control among people with hypertension in rural Thailand.

FACTORSHTN CONTROL (<140/90)HTN CONTROL (OPTIMAL TARGET)*
ADJUSTED PR (95% CI)p-VALUEADJUSTED PR (95% CI)p-VALUE
Sex
    WomenRef.Ref.
    Men1.05 (0.83–1.27)0.6631.00 (0.75–1.24)0.970
Age, years
    20–440.64 (0.29–0.99)0.0460.27 (0.01–0.53)<0.001
    45–651.01 (0.77–1.26)0.9060.64 (0.57–0.71)<0.001
    ≥65Ref.Ref.
Geographical region
    NorthRef.Ref.
    Central0.87 (0.73–1.01)0.0670.84 (0.62–1.05)0.143
    Northeast0.86 (0.72–0.99)0.0340.99 (0.82–1.17)0.928
    South0.78 (0.66–0.91)0.0010.65 (0.57–0.74)<0.001
Health insurance scheme
    Universal health coverageRef.Ref.
    Civil servant medical benefits0.92 (0.64–1.2)0.5550.78 (0.39–1.16)0.256
    Social security1.28 (1.05–1.50)0.0161.41 (0.99–1.83)0.058
    Others1.15 (0.79–1.50)0.4110.88 (0.49–1.27)0.553
Marital status
    MarriedRef.Ref.
    Widowed/divorced0.94 (0.83–1.04)0.2530.78 (0.61–0.95)0.010
    Never married0.61 (0.23–0.99)0.0490.86 (0.59–1.13)0.302
Educational attainment
    Ever education attainmentRef.Ref.
    Never attend0.84 (0.73–0.95)0.0041.01 (0.85–1.16)0.928
Occupation
    No occupation/retiredRef.Ref.
    Farming/agriculture1.08 (0.93–1.24)0.3021.01 (0.85–1.17)0.897
    Others0.88 (0.75–1.01)0.0680.89 (0.71–1.07)0.250
Household income per year, Thai Baht
    Under 50,000Ref.Ref.
    50,000–99,9990.77 (0.61–0.93)0.0050.80 (0.61–0.99)0.036
    100,000–149,9990.85 (0.66–1.05)0.1410.75 (0.56–0.94)0.008
    150,000 and over0.78 (0.60–0.97)0.0260.93 (0.66–1.19)0.576
    No intention to respond1.12 (0.80–1.44)0.4771.53 (1.01–2.04)0.044
Duration of hypertension treatment, years
    1–3Ref.Ref.
    4–61.10 (0.95–1.25)0.2101.12 (0.76–1.48)0.519
    7–91.09 (0.96–1.22)0.1581.36 (0.96–1.75)0.078
    ≥100.92 (0.83–1.00)0.0631.01 (0.71–1.31)0.953
Add extra salt or salty sauce
    1 time per week and lowerRef.Ref.
    2–4 times per week and higher0.62 (0.37–0.87)0.0030.47 (0.18–0.76)<0.001
Physical activity level
    HighRef.Ref.
    Moderate0.98 (0.87–1.09)0.7530.88 (0.73–1.03)0.127
    Low0.29 (0.01–0.75)0.0020.29 (0.01–0.68)<0.001
Sleep duration, hours
    <8Ref.Ref.
    ≥81.08 (0.85–1.30)0.5121.12 (0.75–1.49)0.524
Smoking status
    Never smokerRef.Ref.
    Former smoker1.08 (0.90–1.26)0.4071.14 (0.90–1.39)0.253
    Current smoker1.03 (0.72–1.35)0.8391.00 (0.66–1.35)0.984
Alcohol use
    Lifetime abstainerRef.Ref.
    Former drinker0.93 (0.73–1.12)0.4610.90 (0.72–1.08)0.257
    Current drinker0.93 (0.76–1.11)0.4590.78 (0.50–1.05)0.106
Antihypertensive medication use
    No medication use0.76 (0.45–1.07)0.2390.76 (0.41–1.12)0.191
    Single therapyRef.Ref.
    Dual therapy1.13 (0.99–1.26)0.0831.39 (1.12–1.66)0.004
    Poly therapy1.20 (1.01–1.39)0.0371.43 (1.16–1.70)0.002
Type 2 diabetes
    NoRef.Ref.
    Yes0.92 (0.75–1.08)0.3210.85 (0.61–1.08)0.202
Hyperlipidemia
    NoRef.Ref.
    Yes0.89 (0.54–1.24)0.5331.30 (0.52–2.08)0.451
Chronic kidney disease
    NoRef.Ref.
    Yes0.92 (0.70–1.14)0.4670.86 (0.58–1.14)0.323
Body mass index, kg/m2
    <23.0Ref.Ref.
    23.0–<25.00.93 (0.77–1.08)0.3380.88 (0.71–1.05)0.170
    ≥250.86 (0.74–0.99)0.0280.85 (0.70–0.99)0.035
Psychological stress
    LowRef.Ref.
    Moderate1.02 (0.92–1.11)0.7220.92 (0.77–1.07)0.260
    High0.93 (0.17–2.03)0.8960.97 (0.01–2.30)0.966
Depression
    Non-minimalRef.Ref.
    Mild to moderately severe1.19 (0.98–1.39)0.0791.39 (0.96–1.82)0.074
    Moderate to severe0.99 (0.39–1.58)0.9651.32 (0.67–1.98)0.335
General anxiety
    MinimalRef.Ref.
    Mild to severe1.36 (1.05–1.66)0.0231.10 (0.84–1.37)0.449

[i] *Systolic blood pressure<130 mmHg and diastolic blood pressure <80 mmHg for those aged 20–64 years, systolic blood pressure <140 mmHg and diastolic blood pressure <80 mmHg for those aged 65 years and older.

HTN: hypertension, PR: prevalence ratio, CI: confidence interval.

Table 3

Prevalence of cardiovascular risk factors among people with hypertension in rural Thailand in 2024, stratified by sex, age, and geographical region.

CARDIOVASCULAR RISK FACTORSAGE-ADJUSTED SEX-SPECIFIC WEIGHTED %SEX-ADJUSTED AGE-SPECIFIC WEIGHTED %AGE- AND SEX-ADJUSTED GEOGRAPHICAL REGION-SPECIFIC WEIGHTED %TOTAL
MENWOMEN20–4445–64≥65CENTRALNORTHEASTNORTHSOUTH
Metabolic risk factors
    Dyslipidemia§92.598.710095.697.497.198.094.895.196.5
    High waist to hip ratio (≥0.90 in men and ≥0.85 in women)56.077.090.273.365.982.965.971.773.369.7
    Low HDL cholesterol (<40 mg/dL in men, < 50 mg/dL in women)69.758.267.264.559.0*c55.9‡f54.3†g, †h67.179.962.4
    Abdominal obesity (≥90 cm in men, ≥80 cm in women)35.772.585.271.449.3‡c75.1‡e56.153.0†i68.159.7
    High LDL cholesterol (≥100 mg/dL)56.259.966.069.448.7†c56.465.0*g, †h52.450.958.7
    Obesity (BMI ≥25 kg/m2)41.756.1*89.0*a62.2†b38.759.6‡e52.5*g35.5‡i54.051.5
    High triglyceride (≥150 mg/dL)40.037.836.032.843.744.0*f36.352.4†i28.738.6
    Uncontrolled hypertension (>140/90 mmHg)32.937.079.2†a34.1†b32.940.9†e35.3*g22.5‡i42.536.1
    Diabetes||24.637.7*54.135.829.647.1†e, ‡f40.518.719.433.2
    High total cholesterol (≥200 mg/dL)25.726.355.620.927.824.926.525.524.626.4
    Hyperglycemia (hemoglobin A1c ≥6.5%)16.321.852.819.0‡b17.830.5*e, ‡f23.813.19.020.2
    Hyperglycemia (fasting plasma glucose ≥126 mg/dL)12.816.750.5*a15.5*b12.127.3†e, ‡f15.710.010.515.7
    Chronic kidney disease#4.719.1*1.24.9*b24.2‡c9.6*d,*f22.6†g, ‡h8.85.413.6
Lifestyle risk factors
    Regular salt intake (at least 5–6 times per week)96.596.897.79796.394.3†e, †f95.1†g, †h99.899.896.7
    Abnormal sleep duration (<6 hours or ≥10 hours)11.419.9*7.415.719.514.8*f17.38.9‡i25.216.7
    Current smoker32.11.47.614.58.611.011.111.49.912.5
    Moderate/heavier alcohol drinker (>3 drinks per week)16.53.56.211.24.69.97.210.27.48.2
    Low-level physical activity7.53.5*0‡a2.4‡b7.4*c3.36.31.24.24.9

[i] BMI: body mass index, LDL: low-density lipoprotein. HDL: high-density lipoprotein.

*p < 0.05, p < 0.01, p < 0.001, §Dyslipidemia was defined according to ICD-10 code E78 or a history of lipid-lowering medication use, high TC, high TG, high LDL cholesterol, or low HDL cholesterol, ||Diabetes was defined based on ICD-10 code E11, a history of antihyperglycemic medication use, high FPG, or high HbA1C. #Chronic kidney disease was defined as an estimated glomerular filtration rate <60 mL/min/1.73 m2 or receiving renal replacement therapy.

a20–44 vs. 45–64, b20–44 vs. 65 and older, c45–64 vs. 65 and older, dCentral vs. Northeast, eCentral vs. North, fCentral vs. South, gNortheast vs. North, hNortheast vs. South, iNorth vs. South.

Figure 2

Cardiovascular health status (Life’s Essential 8) among people with hypertension in rural Thailand in 2024, stratified by sex, age, and geographical region.

Figure 3

Prevalence of cardiovascular diseases among people with hypertension in rural Thailand in 2024, stratified by sex (A), age (B), and geographical region (C).

Figure 4

Distribution of predicted 10-year cardiovascular disease (CVD) risk using the World Health Organization laboratory-based risk chart among people with hypertension aged 40–74 without a history of CVD in rural Thailand.

DOI: https://doi.org/10.5334/gh.1515 | Journal eISSN: 2211-8179
Language: English
Submitted on: Aug 17, 2025
Accepted on: Dec 19, 2025
Published on: Dec 31, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Boonsub Sakboonyarat, Kamakshi Lakshminarayan, Ram Rangsin, Mathirut Mungthin, Kanlaya Jongcherdchootrakul, Jaturon Poovieng, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.