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Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017 Cover

Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017

Open Access
|May 2021

Figures & Tables

Table 1

The death cases and age-standardized death rate of aortic aneurysm in 1990 and 2017, and its temporal trends from 1990 to 2017.

Characteristics199020171990–2017
Death cases
No. × 103 (95% UI)
ASR per 100,000
No. (95% UI)
Death cases
No. × 103 (95% UI)
ASR per 100,000
No. (95% UI)
EAPC
No. (95% UI)
Overall104.8 (101.1–110.6)2.88 (2.79–3.03)167.2 (159.8–174.1)2.19 (2.09–2.28)–1.32 (–1.43 to –1.21)
Sex
    Male69.4 (65.6–75.8)4.43 (4.21–4.79)106.3 (100.0–113.8)3.15 (2.97–3.35)–1.59 (–1.71 to –1.48)
    Female35.4 (33.6–39.1)1.75 (1.67–1.92)60.9 (58.7–65.3)1.41 (1.36–1.52)–1.06 (–1.16 to –0.96)
Social-demographic index
    Low5.7 (4.4–7.9)2.08 (1.61–2.79)10.9 (9.2–13.4)1.82 (1.53–2.23)–0.71 (–0.90 to –0.52)
    Low–middle8.6 (7.4–10.5)1.81 (1.56–2.19)19.0 (17.2–21.3)1.85 (1.66–2.07)–0.09 (–0.19 to 0.00)
    Middle12.6 (11.5–14.2)1.57 (1.42–1.75)29.8 (26.9–32.2)1.50 (1.36–1.62)–0.48 (–0.59 to –0.37)
    High–middle18.5 (17.7–19.6)2.12 (2.03–2.25)34.5 (33.1–36.2)2.01 (1.93–2.11)–0.43 (–0.55 to –0.31)
    High59.2 (58.4–60.5)4.47 (4.41–4.56)72.7 (70.8–74.4)2.94 (2.86–3.01)–1.92 (–2.08 to –1.76)
Region
    Central Asia0.6 (0.6–0.7)1.40 (1.24–1.60)1.4 (1.4–1.5)2.19 (2.10–2.28)1.67 (1.52 to 1.82)
    Central Europe3.6 (3.4–3.9)2.47 (2.31–2.66)5.8 (5.5–6.0)2.67 (2.56–2.78)0.43 (0.27 to 0.59)
    Eastern Europe6.9 (6.5–7.3)2.46 (2.33–2.61)10.9 (10.5–11.2)3.15 (3.05–3.26)0.64 (0.40 to 0.87)
    Australasia1.9 (1.8–1.9)7.58 (7.34–7.82)1.7 (1.6–1.8)3.18 (2.91–3.45)–3.86 (–4.09 to –3.64)
    High–income Asia Pacific6.5 (6.4–6.7)3.47 (3.40–3.56)20.6 (19.5–21.4)3.80 (3.61–3.97)0.67 (0.50 to 0.83)
    High–income North America15.0 (14.5–15.5)4.88 (4.81–4.95)18.5 (18.3–18.8)2.35 (2.28–2.43)–3.44 (–3.74 to –3.15)
    Southern Latin America2.7 (2.5–3.0)5.92 (5.46–6.54)3.5 (3.2–3.8)4.15 (3.82–4.53)–1.60 (–1.79 to –1.41)
    Western Europe29.8 (29.2–30.6)4.80 (4.71–4.92)30.9 (29.9–32.0)2.99 (2.89–3.09)–2.25 (–2.51 to –1.99)
    Andean Latin America0.3 (0.3–0.4)1.70 (1.42–2.04)0.8 (0.7–0.9)1.48 (1.34–1.63)–0.58 (–0.68 to –0.48)
    Caribbean1.0 (0.9–1.1)3.80 (3.46–4.21)1.5 (1.4–1.6)2.97 (2.74–3.25)–1.18 (–1.29 to –1.07)
    Central Latin America1.6 (1.6–1.7)2.04 (1.99–2.12)3.5 (3.3–3.7)1.55 (1.47–1.64)–1.53 (–1.72 to –1.35)
    Tropical Latin America3.5 (3.5–3.6)4.06 (3.97–4.15)10.1 (9.6–10.5)4.46 (4.26–4.63)0.12 (–0.02 to 0.26)
    North Africa and Middle East2.4 (2.0–3.5)1.57 (1.30–2.27)5.7 (5.2–7.1)1.51 (1.38–1.91)–0.15 (–0.28 to –0.02)
    South Asia8.0 (6.2–10.9)1.67 (1.34–2.26)21.7 (18.0–25.8)1.91 (1.58–2.26)0.39 (0.24 to 0.53)
    East Asia8.0 (6.5–9.7)0.99 (0.80–1.18)17.4 (15.8–19.2)0.92 (0.83–1.01)–0.53 (–0.67 to –0.39)
    Oceania0.1 (0.1–0.2)4.93 (4.01–6.30)0.2 (0.2–0.3)4.26 (3.50–5.34)–0.79 (–0.90 to –0.68)
    Southeast Asia3.7 (3.3–4.3)1.79 (1.59–2.08)9.0 (8.1–10.2)1.83 (1.64–2.06)–0.19 (–0.31 to –0.07)
    Central Sub–Saharan Africa3.7 (3.3–4.3)4.17 (2.86–5.79)9.0 (8.1–10.2)2.85 (2.21–3.58)–1.79 (–2.02 to –1.57)
    Eastern Sub–Saharan Africa2.2 (1.5–3.0)3.37 (2.24–4.55)2.8 (2.0–3.5)2.09 (1.52–2.67)–2.30 (–2.54 to –2.06)
    Southern Sub–Saharan Africa0.8 (0.6–0.9)3.08 (2.40–3.58)1.2 (1.1–1.4)2.44 (2.27–2.84)–1.24 (–1.87 to –0.61)
    Western Sub–Saharan Africa1.9 (1.5–2.3)2.43 (1.91–2.96)2.5 (2.1–3.1)1.64 (1.35–2.02)–1.88 (–2.11 to –1.66)

[i] ASR: Age-standardized rate; EAPC: Estimated annual percentage change.

Table 2

The DALYs and age-standardized DALYs rate of aneurysm in 1990 and 2017, and its temporal trends from 1990 to 2017.

Characteristics199020171990–2017
DALYs
No. × 103 (95% UI)
ASR per 100,000
No. (95% UI)
DALYs
No. × 103 (95% UI)
ASR per 100,000
No. (95% UI)
EAPC
No. (95% UI)
Overall2089.42 (1996.56–2240.68)51.09 (49.01–54.52)3039.86 (2877.17–3186.41)38.18 (36.21–40)–1.40 (–1.51 to –1.29)
Sex
    Male1457.54 (1370.65–1621.92)78.08 (73.62–86.10)2091.23 (1946.02–2249.36)56.00 (52.27–60.17)–1.56 (–1.67 to –1.44)
    Female631.88 (582.34–731.90)28.83 (26.73–33.15)948.62 (907.06–1049.58)22.34 (21.36–24.74)–1.26 (–1.37 to –1.14)
Social-demographic index
    Low142.67 (103.11–200.88)41.06 (31–56.71)250.79 (209.43–313.40)34.52 (29–42.72)–0.89 (–1.09 to –0.70)
    Low-middle203.55 (169.67–251.85)34.57 (29.41–42.6)421.06 (378.61–475.98)34.89 (31.54–39.3)–0.16 (–0.26 to –0.06)
    Middle299.33 (274.10–345.30)29.69 (27.07–33.75)608.42 (548.59–660.43)27.72 (25.02–30.06)–0.59 (–0.72 to –0.46)
    High-middle430.05 (412.08–459.38)44.17 (42.35–47.05)709.83 (677.80–742.50)39.64 (37.83–41.49)–0.67 (–0.81 to –0.53)
    High1008.90 (993.83–1030.02)77.74 (76.57–79.32)1041.69 (1012.52–1068.82)49.11 (47.71–50.43)–2.07 (–2.22 to –1.91)
Region
    Central Asia15.09 (13.88–16.85)30.11 (27.5–33.86)31.78 (30.37–33.39)42.18 (40.42–44.09)1.19 (1.00 to 1.39)
    Central Europe82.98 (77.44–89.70)55.31 (51.6–59.78)111.01 (105.78–115.58)56.05 (53.43–58.4)0.15 (–0.04 to 0.33)
    Eastern Europe161.14 (151.09–172.25)56.67 (53.1–60.51)234.70 (226.45–242.93)71.73 (69.13–74.43)0.58 (0.31 to 0.85)
    Australasia30.90 (29.85–31.97)125.05 (121.01–129.05)23.20 (21.21–25.33)48.06 (43.89–52.78)–4.18 (–4.41 to –3.96)
    High-income Asia Pacific111.04 (108.60–114.17)54.89 (53.68–56.46)251.43 (237.58–263.76)57.55 (54.23–60.79)0.49 (0.33 to 0.66)
    High-income North America320.64 (315.67–325.75)88.25 (86.85–89.7)249.77 (240.96–258.48)43.99 (42.33–45.64)–3.29 (–3.57 to –3.02)
    Southern Latin America51.75 (47.66–57.30)109.14 (100.63–120.8)59.53 (54.46–65.19)73.37 (67.06–80.34)–1.77 (–1.95 to –1.59)
    Western Europe488.44 (479.16–500.08)82.44 (80.88–84.15)427.70 (411.78–443.29)48.96 (46.95–50.87)–2.43 (–2.67 to –2.18)
    Andean Latin America7.72 (6.38–9.26)33.7 (27.84–40.58)15.24 (13.64–16.93)27.77 (24.82–30.81)–0.74 (–0.85 to –0.63)
    Caribbean17.89 (16.17–19.89)66.57 (60.19–74.11)26.93 (24.68–29.51)53.19 (48.75–58.26)–1.09 (–1.19 to –0.98)
    Central Latin America35.90 (34.89–37.29)39.09 (37.97–40.66)66.74 (62.76–70.82)28.56 (26.87–30.29)–1.69 (–1.87 to –1.51)
    Tropical Latin America89.79 (87.68–92.08)87.73 (85.73–89.92)213.43 (203.49–222.23)90.65 (86.45–94.36)–0.17 (–0.33 to 0.00)
    North Africa and Middle East58.81 (46.17–85.06)31.54 (25.39–45.71)127.84 (116.62–159.71)29.17 (26.58–36.71)–0.30 (–0.41 to –0.19)
    South Asia189.69 (141.74–261.26)31.26 (24.11–42.87)466.14 (388.16–555.97)34.47 (28.6–41.02)0.24 (0.08 to 0.40)
    East Asia203.69 (169.41–258.66)20.59 (16.96–25.63)364.35 (328.39–401.38)18.06 (16.27–19.84)–0.81 (–1.01 to –0.60)
    Oceania3.59 (2.47–4.96)106.02 (78.35–143.28)6.99 (4.95–9.52)91.85 (70.54–120.74)–0.72 (–0.80 to –0.63)
    Southeast Asia83.79 (75.30–101.13)31.62 (28.37–37.55)178.72 (160.53–204.22)31.23 (28.14–35.59)–0.32 (–0.45 to –0.19)
    Central Sub-Saharan Africa19.47 (13.54–28.43)81.53 (56.95–116.06)29.93 (23.17–39.06)56.49 (43.77–72.25)–1.75 (–1.97 to –1.53)
    Eastern Sub-Saharan Africa55.05 (37.53–80.93)66.76 (45.22–94.39)69.82 (51.17–87.19)41.08 (29.88–50.83)–2.35 (–2.60 to –2.10)
    Southern Sub-Saharan Africa18.37 (15.00–20.33)59.57 (47.49–67.47)26.75 (24.63–30.41)46.42 (42.85–53.12)–1.30 (–2.04 to –0.56)
    Western Sub-Saharan Africa43.68 (34.13–53.97)46.48 (36.31–56.84)57.88 (47.83–70.51)30.7 (25.37–37.66)–1.97 (–2.20 to –1.75)

[i] ASR: Age-standardized rate; DALY: Disability-adjusted life year; EAPC: Estimated annual percentage change.

Figure 1

The global deaths burden of AA in 195 countries and territories. A. The absolute number of AA death cases in 2017. B. The ASDR (per 100,000 persons) of AA in 2017. C. The EAPC of AA ASDRs between 1990 and 2017. AA, aortic aneurysm; ASDR, age standardized death rate; EAPC, estimated annual percentage change.

Figure 2

The change trends of ASDR/age-standardized DALY rate (per 100,000 persons) globally and among different SDI quintiles between 1990 and 2017. A. ASDR. B. Age standardized DALY rate. ASDR, age-standardized death rate; DALY, disability-adjusted life year.

Figure 3

The proportion of the three age groups (15–49 years, 50–69 years and 70+ years) for aortic aneurysm deaths globally and in five SDI quintiles between 1990 and 2017. SDI: social-demographic index.

Figure 4

The correlation between the EAPC of deaths/DALYs and (A, B) the corresponding ASRs in 1990 and (C, D) HDI in 2017. The size of circle is increased with the number of death cases of aortic aneurysm. ASR, age-standardized death rate; DALYs, disability-adjusted life years; EAPC, estimated annual percentage change; HDI, human development index.

Figure 5

The proportion of deaths attributable to high systolic blood pressure and smoking globally and in five SDI quintiles between 1990 and 2017. SDI: social-demographic index.

Figure 6

The proportion of deaths attributable to high systolic blood pressure/smoking (A) globally and in 21 GBD regions and (B) in different age groups in 1990 and 2017.

DOI: https://doi.org/10.5334/gh.920 | Journal eISSN: 2211-8179
Language: English
Submitted on: Sep 12, 2020
Accepted on: Mar 26, 2021
Published on: May 4, 2021
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2021 Linyan Wei, Xiang Bu, Xiqiang Wang, Jing Liu, Aiqun Ma, Tingzhong Wang, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.