
Figure 1
Preferred Reporting Items for Systematic Reviews and Meta-Analyses” (PRISMA) flow diagram of the study selection process [25].

Figure 2
Overview of challenges in healthcare provision, components of the interface of collaboration and role distributions as identified from the literature.
HCPs: healthcare professionals; GP: General practitioner.
1: Patient- and disease-related factors refer to challenges in healthcare provision that stem from patient characteristics or characteristics of their conditions. These factors influence the collaboration between specialists and general practitioners, but cannot be modified by the collaboration.
2: Contextual factors originate both from the healthcare system and the collaboration at the primary and secondary care interface, i.e., these factors influence the collaboration between specialists and general practitioners, but can also be modified by this collaboration.
Table 1
Patient population in interventions.
| PATIENT POPULATIONS’ DIAGNOSES | REFERENCES | |
|---|---|---|
| Specific diagnoses | chronic kidney disease (CKD) | 5 projects [26, 27, 37, 38, 39, 40, 41] |
| chronic obstructive pulmonary disorder (COPD) | 3 projects [33, 34, 45, 50] | |
| diabetes type 2 | 2 projects [49, 52, 55] | |
| combination of asthma and COPD | 1 project [47] | |
| chronic hepatitis B | 1 project [53] | |
| chronic heart failure | 1 project [42, 43, 44] | |
| coronary artery disease | 1 project [51] | |
| at least one of the following was present: diabetes, cardiovascular disease, COPD, asthma or cardiovascular risk factors | 1 project [28, 29] | |
| Unspecific patient population (regarding diagnoses) | long-term | 2 projects [36, 46] |
| end of life care | 1 project [32] | |
| multiple chronic conditions | 1 project [30, 31] | |
| heart diseases | 1 project [54] | |
| gastroenterology and hepatology | 1 project [35] | |
| kidney diseases | 1 project [48] |
