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Gut Dysbiosis: Causes and Prevention Strategies – A Review Cover

References

  1. Abd El-Hack M.E., El-Saadony M.T., Elbestawy A.R., Nahed A., Saad A.M., Salem H.M., El-Tahan A.M., Khafaga A.F., Taha A.E., AbuQamar S.F., El-Tarabily K.A. (2022). Necrotic enteritis in broiler chickens: Disease characteristics and prevention using organic antibiotic alternatives: A comprehensive review. Poult. Sci., 101: 101590.
  2. Abdelrahman W., Mohnl M., Teichmann K., Doupovec B., Schatzmayr G., Lumpkins B., Mathis G. (2014). Comparative evaluation of probiotic and salinomycin effects on performance and coccidiosis control in broiler chickens. Poult. Sci., 93: 3002–3008.
  3. Abo El-Maaty H.M.A., Attia Y.A., Alhotan R. A., Al-Banoby M.A., Bovera F., Sherif S.K. (2024). Impact of early feed restriction and continued supplementation with coated organic acids and essential oils on the sustainability of laying performance, egg quality, fertility, hatchability, immunity status, and gut microbiota of Japanese quail hens. Ann. Anim. Sci., 24: 503–517.
  4. Adil S., Magray S.N. (2012). Impact and manipulation of gut micro-flora in poultry: a review. J. Anim. Vet. Adv., 11: 873–877.
  5. Ahmad R., Yu Y.H., Hua K.F., Chen W.J., Zaborski D., Dybus A., Hsiao F.S.H., Cheng Y.H. (2024). Management and control of coccidiosis in poultry – a review. Anim. Biosci., 37: 1.
  6. Akinyemi F.T., Ding J., Zhou H., Xu K., He C., Han C., Zheng Y., Luo H., Yang K., Gu C., Huang Q. (2020). Dynamic distribution of gut microbiota during embryonic development in chicken. Poult. Sci., 99: 5079–5090.
  7. Al-Khalaifa H., Al-Nasser A., Al-Surayee T., Al-Kandari S., Al-Enzi N., Al-Sharrah T., Ragheb G., Al-Qalaf S., Mohammed A. (2019). Effect of dietary probiotics and prebiotics on the performance of broiler chickens. Poult. Sci., 98: 4465–4479.
  8. Attia Y.A., Abd-El-Rahman S.A. (2001). Impact of multienzymes or Yea Sacc supplementation on growth performance and some carcass parameters of broiler chicks fed triticale containing diets. Eur. Poult. Sci., 65: 168–177.
  9. Attia Y.A., Hassan S.S. (2017). Broiler tolerance to heat stress at various dietary protein/energy levels. Eur. Poult. Sci., 81: 171.
  10. Attia Y.A., Ellakany H.F., El-Hamid A.A., Bovera F., Ghazaly S. (2012). Control of Salmonella enteritidis infection in male layer chickens by acetic acid and/or prebiotics, probiotics and antibiotics. Eur. Poult. Sci., 76: 239–245.
  11. Attia Y.A., Allakany H.F., Abd Al-Hamid A.E., Al-Saffar A.A., Hassan R.A., Mohamed N.A. (2013). Capability of different non-nutritive feed additives on improving productive and physiological traits of broiler chicks fed diets with or without aflatoxin during the first 3 weeks of life. J. Anim. Physiol. Anim. Nutr., 97: 754–772.
  12. Attia Y.A., Abd Al-Hamid A.E., Allakany H.F., Al-Harthi M.A., Mohamed N.A. (2016). Necessity of continuing of supplementation of non-nutritive feed additive during days 21–42 of age following 3 weeks of feeding aflatoxin to broiler chickens. J. Appl. Anim. Res., 44: 87–98.
  13. Attia Y.A., Al-Harthi M.A., El-Shafey A.S., Rehab Y.A., Kim W.K. (2017). Enhancing tolerance of broiler chickens to heat stress by supplementation with vitamin E, vitamin C and/or probiotics. Ann. Anim. Sci., 17: 1155–1169.
  14. Attia Y.A., Al-Harthi M.A., Elnaggar A.S. (2018). Productive, physiological and immunological responses of two broiler strains fed different dietary regimens and exposed to heat stress. Ital. J. Anim. Sci., 17: 686–697.
  15. Attia Y.A., Abo El-Maaty H.M., Alhotan R.A., Bovera F., Sherif S.K. (2023). Coated organic acids with essential oils in Japanese quail’s fed restricted during the 2nd week of age: effects on performance, carcase traits, blood profile, antioxidants status, and caeca micro-biota. Ital. J. Anim. Sci., 22: 816–828.
  16. Aya V., Flóre A., Perez, L., Ramírez J.D. (2021). Association between physical activity and changes in intestinal microbiota composition: A systematic review. PLoS One, 16: 0247039.
  17. Azad K.M., Kikusato M., Hoque A.M., Toyomizu M. (2010). Effect of chronic heat stress on performance and oxidative damage in different strains of chickens. J. Poult. Sci., 47: 333–337.
  18. Bindari Y.R., Gerber P.F. (2022). Centennial Review: Factors affecting the chicken gastrointestinal microbial composition and their association with gut health and productive performance. Poult. Sci., 101: 101612.
  19. Blachier F., Beaumont M., Portune K.J., Steuer N., Lan A., Audebert M., Khodorova N., Andriamihaja M., Airinei G., Benamouzig R., Davila A.M. (2019). High-protein diets for weight management: Interactions with the intestinal microbiota and consequences for gut health. A position paper by my new gut study group. Clin. Nutr., 38: 1012–1022.
  20. Blekhman R., Goodrich J.K., Huang K., Sun Q., Bukowski R., Bell J.T., Spector T.D., Keinan A., Ley R.E., Gevers D., Clark A.G. (2015). Host genetic variation impacts microbiome composition across human body sites. Genome Biol., 16: 1–12.
  21. Brown K., DeCoffe D., Molcan E., Gibson D.L. (2012). Diet-induced dysbiosis of the intestinal microbiota and the effects on immunity and disease. Nutrients, 4: 1095–1119.
  22. Chattopadhyay M.K. (2014). Use of antibiotics as feed additives: a burning question. Front. Microbiol., 5: 334.
  23. Chen C., Chen W., Ding H., Wu P., Zhan, G., Xie K., Zhang T. (2023). High-fat diet-induced gut microbiota alteration promotes lipo-genesis by butyric acid/miR-204/ACSS2 axis in chickens. Poult. Sci., 102: 102856.
  24. Chen Y., Ni J., Li H. (2019). Effect of green tea and mulberry leaf powders on the gut microbiota of chicken. BMC Vet. Res., 15: 1–6.
  25. Costa M.C., Bessegatto J.A., Alfieri A.A., Weese J.S., Filho J.A., Oba A. (2017). Different antibiotic growth promoters induce specific changes in the cecal microbiota membership of broiler chicken. PLoS One, 12: 0171642.
  26. de Freitas L.F.V.B., Sakomura N.K., de Paula Reis M., Mariani A.B., Lambert W., Andretta I., Létourneau-Montminy M.P. (2023). Coccidiosis infection and growth performance of broilers in experimental trials: insights from a meta-analysis including modulating factors. Poult. Sci., 102: 103021.
  27. De Grande A., Leleu S., Delezie E., Rapp C., De Smet S., Goossens E., Haesebrouck F., Van Immerseel F., Ducatelle R. (2020). Dietary zinc source impacts intestinal morphology and oxidative stress in young broilers. Poult. Sci., 99: 441–453.
  28. De Gussem M. (2007). Coccidiosis in poultry: review on diagnosis, control, prevention and interaction with overall gut health. Proc. 16th European Symposium on Poultry Nutrition, pp. 253–261.
  29. Demas G.E., Zysling D.A., Beechler B.R., Muehlenbein M.P., French S.S. (2011). Beyond phytohaemagglutinin: assessing vertebrate immune function across ecological contexts. J. Anim. Ecol., 80: 710–730.
  30. Desbruslais A., Wealleans A.L. (2022). Oxidation in poultry feed: impact on the bird and the efficacy of dietary antioxidant mitigation strategies. Poultry, 1: 246–277.
  31. Diaz Carrasco J.M., Casanova N.A., Fernández Miyakawa M.E. (2019). Microbiota, gut health and chicken productivity: what is the connection?. Microorganisms, 7: 374.
  32. Ducatelle R., Goossens E., Eeckhaut V., Van Immerseel F. (2023). Poultry gut health and beyond. Anim. Nutr., 13: 240–248.
  33. Elokil A.A., Abouelezz K.F., Ahmad H.I., Pan Y., Li S. (2020). Investigation of the impacts of antibiotic exposure on the diversity of the gut microbiota in chicks. Animals, 10: 896.
  34. Fernández J., Redondo-Blanco S., Gutiérrez-del-Río I., Miguélez E.M., Villar C.J., Lombo F. (2016). Colon microbiota fermentation of dietary prebiotics towards short-chain fatty acids and their roles as anti-inflammatory and antitumour agents: A review. J. Funct. Foods, 25: 511–522.
  35. Gadde U., Kim W.H., Oh S.T., Lillehoj H.S. (2017). Alternatives to antibiotics for maximizing growth performance and feed efficiency in poultry: a review. Anim. Health Res. Rev., 18: 26–45.
  36. Gilbert J.A., Blaser M.J., Caporaso J.G., Jansson J.K., Lynch S.V., Knight R. (2018). Current understanding of the human microbiome. Nat. Med., 24: 392–400.
  37. Greene G., Koolman L., Whyte P., Burgess C., Bolton D. (2023). The gut microbiota of broilers reared with and without antibiotic treatment. Microorganisms, 11: 876.
  38. Habashy W.S., Milfort M.C., Adomako K., Attia Y.A., Rekaya R., Aggrey S.E. (2017). Effect of heat stress on amino acid digestibility and transporters in meat-type chickens. Poult. Sci., 96: 2312–2319.
  39. Hafez H.M., Attia Y.A. (2020). Challenges to the poultry industry: current perspectives and strategic future after the COVID-19 outbreak. Front. Vet. Sci., 7: 516.
  40. Hossain M.J., Attia Y.A., Ballah F.M., Islam M.S., Sobur M.A., Islam M.A., Ievy S., Rahman A., Nishiyama A., Islam M.S., Hassan J. (2021). Zoonotic significance and antimicrobial resistance in Salmonella in poultry in Bangladesh for the period of 2011–2021. Zoonoticdis, 1: 3–24.
  41. Huang P., Zhang Y., Xiao K., Jiang F., Wang H., Tang D., Liu D., Liu B., Liu Y., He X., Liu H. (2018). The chicken gut metagenome and the modulatory effects of plant-derived benzylisoquinoline alkaloids. Microbiome, 6: 1–17.
  42. Inoue R., Ohue-Kitano R., Tsukahara T., Tanaka M., Masuda S., Inoue T., Yamakage H., Kusakabe T., Hasegawa K., Shimatsu A. Satoh-Asahara N. (2017). Prediction of functional profiles of gut micro-biota from 16S rRNA metagenomic data provides a more robust evaluation of gut dysbiosis occurring in Japanese type 2 diabetic patients. J. Clin. Biochem. Nutr., 61: 217–221.
  43. Kailasapathy K., Chin J. (2000). Survival and therapeutic potential of probiotic organisms with reference to Lactobacillus acidophilus and Bifidobacterium spp. Immunol. Cell Biol., 78: 80–88.
  44. Kellam P., Weiss R.A. (2006). Infectogenomics: insights from the host genome into infectious diseases. Cell, 124: 695–697.
  45. Kogut M.H. (2019). Understanding gut function in poultry: the role of commensals, metabolites, inflammation and dysbiosis in intestinal immune function and dysfunction. In: Improving gut health in poultry. Burleigh Dodds Sci. Pub., pp. 143–162.
  46. Kogut M.H., Lee A., Santin E. (2020). Microbiome and pathogen interaction with the immune system. Poult. Sci., 99: 1906–1913.
  47. Lambert G.P. (2009). Stress-induced gastrointestinal barrier dysfunction and its inflammatory effects. J. Anim. Sci., 87: 101–108.
  48. Lee K.W., Hong Y.H., Lee S.H., Jang S.I., Park M.S., Bautista D.A., Ritter G.D., Jeong W., Jeoung H.Y., An D.J., Lillehoj E.P. (2012). Effects of anticoccidial and antibiotic growth promoter programs on broiler performance and immune status. Res. Vet. Sci., 93: 721–728.
  49. Li A., Wang Y., Kulyar M.F.E.A., Iqbal M., Lai R., Zhu H., Li K. (2023). Environmental microplastics exposure decreases antioxidant ability, perturbs gut microbial homeostasis and metabolism in chicken. Sci. Total Environ., 856: 159089.
  50. Li W., Xu B., Wang L., Sun Q., Deng W., Wei F., Ma H., Fu C., Wang G., Li S. (2021). Effects of Clostridium butyricum on growth performance, gut microbiota and intestinal barrier function of broilers. Front. Microbiol., 12: 777456.
  51. Liew W.P.P., Mohd-Redzwan S. (2018). Mycotoxin: Its impact on gut health and microbiota. Front. Cell. Infect. Microbiol., 8: 60. Lilburn M.S., Loeffler S. (2015). Early intestinal growth and development in poultry. Poult. Sci., 94: 1569–1576.
  52. Lin J. (2014). Antibiotic growth promoters enhance animal production by targeting intestinal bile salt hydrolase and its producers. Front. Microbiol, 5: 33.
  53. Ma J., Piao X., Mahfuz S., Long S., Wang J. (2022). The interaction among gut microbes, the intestinal barrier and short chain fatty acids. Anim. Nutr., 9: 159–174.
  54. Magnoli A.P., Monge M.P., Miazzo R.D., Cavaglieri L.R., Magnoli C.E., Merkis C.I., Cristofolini A.L., Dalcero A.M., Chiacchiera S.M. (2011). Effect of low levels of aflatoxin B1 on performance, biochemical parameters, and aflatoxin B1 in broiler liver tissues in the presence of monensin and sodium bentonite. Poult. Sci., 90: 48–58.
  55. Maharjan P., Martinez D.A., Weil J., Suesuttajit N., Umberson C., Mullenix G., Hilton K.M., Beitia A., Coon C.N. (2021). Physiological growth trend of current meat broilers and dietary protein and energy management approaches for sustainable broiler production. Animal, 15: 100284.
  56. Marttinen M., Ala-Jaakkola R., Laitila A., Lehtinen M.J. (2020). Gut microbiota, probiotics and physical performance in athletes and physically active individuals. Nutrients, 12: 2936.
  57. Mehdi Y., Létourneau-Montminy M.P., Gaucher M.L., Chorfi Y., Suresh G., Rouissi T., Brar S.K., Côté C., Ramirez A.A., Godbout S. (2018). Use of antibiotics in broiler production: Global impacts and alternatives. Anim. Nutr., 4: 170–178.
  58. Mullish B.H., Pechlivanis A., Barker G. F., Thursz M.R., Marchesi J.R., McDonald J.A. (2018). Functional microbiomics: evaluation of gut microbiota-bile acid metabolism interactions in health and disease. Methods, 149: 49–58.
  59. Murugesan G.R., Ledoux D.R., Naehrer K., Berthiller F., Applegate T.J., Grenier B., Phillips T.D., Schatzmayr G. (2015 a). Prevalence and effects of mycotoxins on poultry health and performance, and recent development in mycotoxin counteracting strategies. Poult. Sci., 94: 1298–1315.
  60. Murugesan G.R., Syed B., Haldar S., Pender C. (2015 b). Phytogenic feed additives as an alternative to antibiotic growth promoters in broiler chickens. Front. Vet. Sci., 2: 21.
  61. Nallala V., Sadishkumar V., Jeevaratnam K. (2017). Molecular characterization of antimicrobial Lactobacillus isolates and evaluation of their probiotic characteristics in vitro for use in poultry. Food Biotechnol., 31: 20–41.
  62. Nibali L., Henderson B., Tariq Sadiq S., Donos N. (2014). Genetic dysbiosis: the role of microbial insults in chronic inflammatory diseases. J. Oral Microbiol., 6: 22962.
  63. Oakley B.B., Lillehoj H.S., Kogut M.H., Kim W.K., Maurer J.J., Pedroso A., Lee M.D., Collett S.R., Johnson T.J., Cox N.A. (2014). The chicken gastrointestinal microbiome. FEMS Microbiol. Let., 360: 100–112.
  64. Pan D., Yu Z. (2014). Intestinal microbiome of poultry and its interaction with host and diet. Gut Microbes, 5: 108–119.
  65. Panda A.K., Cherian G. (2014). Role of vitamin E in counteracting oxidative stress in poultry. J. Poult. Sci., 51: 109–117.
  66. Pickard J.M., Zeng M.Y., Caruso R., Núñez G. (2017). Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease. Immunol. Rev., 279: 70–89.
  67. Pires P. G. S., Oliveira G.S., McManus C., Santos V.M., Moraes P.O. (2024). Impact of housing system on intestinal microbiota of laying hens – a systematic review. Res. Vet. Sci., 105184.
  68. Ringseis R., Eder K. (2022). Heat stress in pigs and broilers: role of gut dysbiosis in the impairment of the gut-liver axis and restoration of these effects by probiotics, prebiotics and synbiotics. J. Anim. Sci. Biotechnol., 13: 126.
  69. Rinninella E., Raoul P., Cintoni M., Franceschi F., Miggiano G.A.D., Gasbarrini A., Mele M.C. (2019). What is the healthy gut microbiota composition? A changing ecosystem across age, environment, diet, and diseases. Microorganisms, 7: 14.
  70. Robinson K., Becker S., Xiao Y., Lyu W., Yang Q., Zhu H., Yang H., Zhao J., Zhang G. (2019). Differential impact of subtherapeutic antibiotics and ionophores on intestinal microbiota of broilers. Microorganisms, 7: 282.
  71. Ronquillo M.G., Hernandez J.C.A. (2017). Antibiotic and synthetic growth promoters in animal diets: review of impact and analytical methods. Food Control, 72: 255–267.
  72. Sanganyado E., Gwenzi W. (2019). Antibiotic resistance in drinking water systems: Occurrence, removal, and human health risks. Sci. Total Environ., 669: 785–797.
  73. Sarangi A. N., Goel A., Aggarwal R. (2019). Methods for studying gut microbiota: a primer for physicians. J. Clin. Exp. Hepatol., 9: 62–73.
  74. Shanmugasundaram R., Lourenco J., Hakeem W.A., Dycus M.M., Applegate T.J. (2023). Subclinical doses of dietary fumonisins and deoxynivalenol cause cecal microbiota dysbiosis in broiler chickens challenged with Clostridium perfringens. Front. Micro-biol., 14: 1106604.
  75. Shaufi M.A. M., Sieo C.C., Chong C.W., Geok Hun T., Omar A.R., Han Ming G., Wan Ho Y. (2023). Effects of phage cocktail, probiotics, and their combination on growth performance and gut microbiota of broiler chickens. Animals, 13: 1328.
  76. Shehata A.A., Yalçın S., Latorre J.D., Basiouni S., Attia Y.A., Abd El-Wahab A., Visscher C., El-Seedi H.R., Huber C., Hafez H.M., Eisenreich W. (2022). Probiotics, prebiotics, and phytogenic substances for optimizing gut health in poultry. Microorganisms, 10: 395.
  77. Shi D., Bai L., Qu Q., Zhou S., Yang M., Guo S., Li Q., Liu C. (2019). Impact of gut microbiota structure in heat-stressed broilers. Poult. Sci., 98: 2405–2413.
  78. Siddiqui M.T., Cresci G.A. (2021). The immunomodulatory functions of butyrate. J. Inflamm. Res., 14: 6025–6041.
  79. Skvortsova L.N., Koshchaev A.G., Shcherbatov V.I., Lysenko Y. A., Fisinin V. I., Saleeva I.P., Sukhanova S.F. (2018). The use of probiotics for improving the biological potential of broiler chickens. Int. J. Pharm. Res., 10: 760.
  80. Smith J.A. (2019). Broiler production without antibiotics: United States field perspectives. Anim. Feed Sci. Technol., 250: 93–98.
  81. Stanley D., Hughes R.J., Geier M.S., Moore R.J. (2016). Bacteria within the gastrointestinal tract microbiota correlated with improved growth and feed conversion: challenges presented for the identification of performance enhancing probiotic bacteria. Front. Microbiol., 7: 187.
  82. Taheri H.R., Moravej H., Tabandeh F., Zaghari M., Shivazad M. (2009). Screening of lactic acid bacteria towards their selection as a source of chicken probiotic. Poult. Sci., 88: 1586–1593.
  83. Takiishi T., Fenero C.I.M., Câmara N.O.S. (2017). Intestinal barrier and gut microbiota: Shaping our immune responses throughout life. Tissue Barriers, 5: 1373208.
  84. Taylor-Bowden T., Bhogoju S., Khwatenge C.N., Nahashon S.N. (2024). The impact of essential amino acids on the gut microbiota of broiler chickens. Microorganisms, 1: 693.
  85. Tůmová E., Chodová D., Skřivanová E., Laloučková K., Šubrtová-Salmonová H., Ketta M., Machander V., Cotozzolo E. (2021). Research note: The effects of genotype, sex, and feeding regime on performance, carcasses characteristic, and microbiota in chickens. Poult. Sci., 10: 760–764.
  86. Veldhuizen E.J., Brouwer E.C., Schneider V.A., Fluit A.C. (2013). Chicken cathelicidins display antimicrobial activity against multiresistant bacteria without inducing strong resistance. PLOS one, 8: 61964.
  87. Wan S., Sun N., Li H., Khan A., Zheng X., Sun Y., Fan R. (2022). Deoxynivalenol damages the intestinal barrier and biota of the broiler chickens. BMC Vet. Res., 18: 311.
  88. Wang A., Hogan N.S. (2019). Performance effects of feed-borne Fusarium mycotoxins on broiler chickens: Influences of timing and duration of exposure. Anim. Nutr., 5: 32–40.
  89. Wang L., Lin Z., Ali M., Zhu X., Zhang Y., Li S., Li K., Kebzhai F., Li J. (2023). Effects of lactic acid bacteria isolated from Tibetan chickens on the growth performance and gut microbiota of broiler. Front. Microbiol., 14: 1171074.
  90. Webster A.J.F., Tuddenham A., Saville C.A., Scott G.B. (1993). Thermal stress on chickens in transit. Br. Poult. Sci., 34: 267–277. Wei L., Singh R., Ro S., Ghoshal U.C. (2021). Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology. JGH Open, 5: 976–987.
  91. Wen C., Yan W., Sun C., Ji C., Zhou Q., Zhang D., Zheng J., Yang N. (2019). The gut microbiota is largely independent of host genetics in regulating fat deposition in chickens. ISME J., 13: 1422–1436.
  92. Wen C., Yan W., Mai C., Duan Z., Zheng J., Sun C., Yang N. (2021). Joint contributions of the gut microbiota and host genetics to feed efficiency in chickens. Microbiome, 9: 1–23.
  93. Wickramasuriya S.S., Park I., Lee, Y., Richer L.M., Przybyszewski C., Gay C.G., Van Oosterwijk J.G., Lillehoj H.S. (2023). Orally delivered Bacillus subtilis expressing chicken NK-2 peptide stabilizes gut microbiota and enhances intestinal health and local immunity in coccidiosis-infected broiler chickens. Poult. Sci., 102: 102590.
  94. Wilson J., Tice G., Brash M.L., Hilaire S.S. (2005). Manifestations of Clostridium perfringens and related bacterial enteritides in broiler chickens. Worlds Poult. Sci. J., 61: 435–449.
  95. Xi Y., Yan J., Li M., Ying S., Shi Z. (2019). Gut microbiota dysbiosis increases the risk of visceral gout in goslings through translocation of gut-derived lipopolysaccharide. Poult. Sci., 98: 5361–5373.
  96. Yacoub H.A., Elazzazy A.M., Abuzinadah O.A., Al-Hejin A.M., Mahmoud M.M., Harakeh S.M. (2015). Antimicrobial activities of chicken β-defensin (4 and 10) peptides against pathogenic bacteria and fungi. Front. Cell. Infect. Microbiol., 5: 36.
  97. Yang X.J., Li W.L., Feng Y., Yao J.H. (2011). Effects of immune stress on growth performance, immunity, and cecal microflora in chickens. Poult. Sci., 90: 2740–2746.
  98. Yunus A.W., Razzazi-Fazeli E., Bohm J. (2011). Aflatoxin B1 in affecting broiler’s performance, immunity, and gastrointestinal tract: A review of history and contemporary issues. Toxins, 3: 566–590.
  99. Zhu L., Liao R., Wu N., Zhu G., Yang C. (2019). Heat stress mediates changes in fecal microbiome and functional pathways of laying hens. Appl. Microbiol. Biotechnol., 103: 461–472.
  100. Zhu Q., Sun P., Zhang B., Kong L., Xiao C., Song Z. (2021). Progress on gut health maintenance and antibiotic alternatives in broiler chicken production. Front. Nutr., 8: 692839.
  101. Zihler A., Gagnon M., Chassard C., Hegland A., Stevens M.J., Braegger C.P., Lacroix C. (2010). Unexpected consequences of administering bacteriocinogenic probiotic strains for Salmonella populations, revealed by an in vitro colonic model of the child gut. Microbiology, 156: 3342–3353.
DOI: https://doi.org/10.2478/aoas-2025-0018 | Journal eISSN: 2300-8733 | Journal ISSN: 1642-3402
Language: English
Page range: 1297 - 1311
Submitted on: Oct 17, 2024
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Accepted on: Jan 9, 2025
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Published on: Oct 24, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: Volume open

© 2025 Youssef A. Attia, Ibrahim E. Helal, Sameer A. Nagadi, Asmaa F. Khafaga, Ayman E. Taha, Khalid A. Asiry, Nisreen M. Abdulsalam, Nidal M. Zabermawi, Manal E. Shafi, Hana A. Zakaria, Tarek A. Ebeid, Ibrahim H. Al-Homidan, Fulvia Bovera, Vincenzo Tufarelli, published by National Research Institute of Animal Production
This work is licensed under the Creative Commons Attribution 4.0 License.