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The Risk of Orofacial Cleft Lip/Palate Due to Maternal Ambient Air Pollution Exposure: A Call for Further Research in South Africa Cover

The Risk of Orofacial Cleft Lip/Palate Due to Maternal Ambient Air Pollution Exposure: A Call for Further Research in South Africa

Open Access
|Jan 2023

Figures & Tables

Table 1

Overview of PM2.5 and PM10 annual average data at South African Ambient Air Quality Monitoring Stations at 50% data availability (South African National Ambient Air Quality Standards (NAAQS) current limit values for annual averages: PM2.5 = 20 µg/m3; PM10 = 40 µg/m3).

PM2.5PM10
PROVINCESTATIONS PER PROVINCE*MEAN ± STD DEVMEDIAN ± IQRSTATIONS PER PROVINCE*MEAN ± STD DEVMEDIAN ± IQR
Eastern Cape49 (4)11 (2)521 (9)23 (8)
Free State534 (8)32 (8)570 (25)59 (36)
Gauteng1535 (18)32 (11)2559 (25)55 (23)
KwaZulu-Natal1119 (13)17 (5)1432 (13)28 (17)
Limpopo818 (13)14 (7)839 (19)32 (24)
Mpumalanga2223 (8)22 (8)2651 (21)50 (26)
North-West425 (20)14 (12)444 (18)42 (36)
Northern Cape14 (–)– (–)17 (–)–(–)
Western Cape410 (5)8 (4)1030 (9)31 (11)

[i] * Number of stations which met the > 50% data availability threshold at least once over the period. Not all stations had data every year.

Figure 1

Scatter plots of average annual (A) PM2.5 and (B) PM10 and CLP birth prevalence per 1,000 live births from 2006 to 2020. The dashed blue vertical lines represent the current South African NAAQS of 20 and 40 µg/m3 for annual PM2.5 and PM10, respectively.

Figure 2

Location of all CLP cases in our dataset overlaid by the findings of hot and cold spots of CLP birth prevalence per 1,000 live births by district municipality. The table for CLP birth prevalence for each district municipality per 1,000 live births is given in the Supplementary Material.

DOI: https://doi.org/10.5334/aogh.4007 | Journal eISSN: 2214-9996
Language: English
Submitted on: Nov 3, 2022
Accepted on: Dec 29, 2022
Published on: Jan 27, 2023
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2023 Caradee Y. Wright, Thandi Kapwata, Bianca Wernecke, Helen Malherbe, Kurt-W Bütow, Natasha Naidoo, Rebecca M. Garland, Anzel de Lange, Gareth E. Murray, Operation Smile, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.